Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028000157> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2028000157 endingPage "832" @default.
- W2028000157 startingPage "825" @default.
- W2028000157 abstract "Abstract This method describes the simultaneous separation, identification, quantification and confirmation of betamethasone (BTM) and dexamethasone (DXM) in equine plasma by liquid chromatography (LC) integrated with multidimensional tandem mass spectrometry. Analytes were directly extracted from equine plasma by methyl tert ‐butyl ether (MTBE). The residues were reconstituted with sample solvent. LC separation of the analytes was performed on a Hypercarb column using acetonitrile/water/formic acid (95:5:0.5, v/v/v) as the mobile phase. Sample screening, quantification and confirmation were performed in multiple reaction monitoring (MRM) mode. The method was linear over the concentration range of 0.1–75 ng/mL for both analytes. Limit of detection (LOD) was 50 pg/mL and that of quantification (LOQ) was 100 pg/mL for both analytes. The limit of confirmation (LOC) for the presence of BTM or DXM by MRM was 0.5 ng/mL. The intra‐and inter‐day precisions expressed as coefficient of variation (CV) for quantification of DXM and BTM from 0.1 to 50 ng/mL were less than 7% and the accuracy was in the range of 97–105%. This method is capable of distinguishing BTM from DXM when both analytes are simultaneously present in equine plasma. Measurement uncertainty for both analytes was estimated at less than 16%. The method is rapid, specific, selective, sensitive, simple and reliable. The importance of this method is its usefulness in directly identifying and differentiating BTM from DXM without derivatization. Copyright © 2005 John Wiley & Sons, Ltd." @default.
- W2028000157 created "2016-06-24" @default.
- W2028000157 creator A5026810796 @default.
- W2028000157 creator A5031682545 @default.
- W2028000157 creator A5052665610 @default.
- W2028000157 creator A5058012260 @default.
- W2028000157 creator A5061708745 @default.
- W2028000157 creator A5079810527 @default.
- W2028000157 date "2005-02-15" @default.
- W2028000157 modified "2023-10-15" @default.
- W2028000157 title "Resolution, quantification and confirmation of betamethasone and dexamethasone in equine plasma by liquid chromatography/tandem mass spectrometry" @default.
- W2028000157 cites W1964320132 @default.
- W2028000157 cites W1972072699 @default.
- W2028000157 cites W2008241453 @default.
- W2028000157 cites W2010440073 @default.
- W2028000157 cites W2017726146 @default.
- W2028000157 cites W2025598122 @default.
- W2028000157 cites W2040665865 @default.
- W2028000157 cites W2052307558 @default.
- W2028000157 cites W2071540896 @default.
- W2028000157 cites W2072870955 @default.
- W2028000157 cites W2077567574 @default.
- W2028000157 cites W2162410798 @default.
- W2028000157 cites W2164647900 @default.
- W2028000157 cites W3006182500 @default.
- W2028000157 doi "https://doi.org/10.1002/rcm.1851" @default.
- W2028000157 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15714597" @default.
- W2028000157 hasPublicationYear "2005" @default.
- W2028000157 type Work @default.
- W2028000157 sameAs 2028000157 @default.
- W2028000157 citedByCount "43" @default.
- W2028000157 countsByYear W20280001572012 @default.
- W2028000157 countsByYear W20280001572013 @default.
- W2028000157 countsByYear W20280001572014 @default.
- W2028000157 countsByYear W20280001572018 @default.
- W2028000157 countsByYear W20280001572020 @default.
- W2028000157 countsByYear W20280001572021 @default.
- W2028000157 countsByYear W20280001572022 @default.
- W2028000157 crossrefType "journal-article" @default.
- W2028000157 hasAuthorship W2028000157A5026810796 @default.
- W2028000157 hasAuthorship W2028000157A5031682545 @default.
- W2028000157 hasAuthorship W2028000157A5052665610 @default.
- W2028000157 hasAuthorship W2028000157A5058012260 @default.
- W2028000157 hasAuthorship W2028000157A5061708745 @default.
- W2028000157 hasAuthorship W2028000157A5079810527 @default.
- W2028000157 hasConcept C10390740 @default.
- W2028000157 hasConcept C119128265 @default.
- W2028000157 hasConcept C137535248 @default.
- W2028000157 hasConcept C138268822 @default.
- W2028000157 hasConcept C154945302 @default.
- W2028000157 hasConcept C162356407 @default.
- W2028000157 hasConcept C185592680 @default.
- W2028000157 hasConcept C2776923573 @default.
- W2028000157 hasConcept C2777379063 @default.
- W2028000157 hasConcept C2778576202 @default.
- W2028000157 hasConcept C31827203 @default.
- W2028000157 hasConcept C41008148 @default.
- W2028000157 hasConcept C43617362 @default.
- W2028000157 hasConcept C64489805 @default.
- W2028000157 hasConcept C71043704 @default.
- W2028000157 hasConcept C89838059 @default.
- W2028000157 hasConceptScore W2028000157C10390740 @default.
- W2028000157 hasConceptScore W2028000157C119128265 @default.
- W2028000157 hasConceptScore W2028000157C137535248 @default.
- W2028000157 hasConceptScore W2028000157C138268822 @default.
- W2028000157 hasConceptScore W2028000157C154945302 @default.
- W2028000157 hasConceptScore W2028000157C162356407 @default.
- W2028000157 hasConceptScore W2028000157C185592680 @default.
- W2028000157 hasConceptScore W2028000157C2776923573 @default.
- W2028000157 hasConceptScore W2028000157C2777379063 @default.
- W2028000157 hasConceptScore W2028000157C2778576202 @default.
- W2028000157 hasConceptScore W2028000157C31827203 @default.
- W2028000157 hasConceptScore W2028000157C41008148 @default.
- W2028000157 hasConceptScore W2028000157C43617362 @default.
- W2028000157 hasConceptScore W2028000157C64489805 @default.
- W2028000157 hasConceptScore W2028000157C71043704 @default.
- W2028000157 hasConceptScore W2028000157C89838059 @default.
- W2028000157 hasIssue "6" @default.
- W2028000157 hasLocation W20280001571 @default.
- W2028000157 hasLocation W20280001572 @default.
- W2028000157 hasOpenAccess W2028000157 @default.
- W2028000157 hasPrimaryLocation W20280001571 @default.
- W2028000157 hasRelatedWork W2087241326 @default.
- W2028000157 hasRelatedWork W2134717147 @default.
- W2028000157 hasRelatedWork W2185025379 @default.
- W2028000157 hasRelatedWork W2376992728 @default.
- W2028000157 hasRelatedWork W2798103833 @default.
- W2028000157 hasRelatedWork W2891353621 @default.
- W2028000157 hasRelatedWork W2922172189 @default.
- W2028000157 hasRelatedWork W4251012885 @default.
- W2028000157 hasRelatedWork W4280604482 @default.
- W2028000157 hasRelatedWork W4318755472 @default.
- W2028000157 hasVolume "19" @default.
- W2028000157 isParatext "false" @default.
- W2028000157 isRetracted "false" @default.
- W2028000157 magId "2028000157" @default.
- W2028000157 workType "article" @default.