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- W2028004022 abstract "Postprandial lipaemia refers to the accumulation of triglyceride-rich lipoprotein particles (chylomicron, VLDL and their remnants) in plasma approximately 6–10 h after a fatty meal. Chylomicron remnant particles, in particular, are atherogenic, owing to the induction of endothelial dysfunction and increased delivery of cholesterol to the subendothelial space [ [1] Watts G.F. Mamo J.C.L. Postprandial dyslipidaemia: new opportunities for prevention of coronary disease?. Br. J. Cardiol. 1998; 5: 260-264 Google Scholar ]. It is important to note that the absolute amount of cholesterol transported per unit time in plasma, in the chylomicron remnant particle in plasma, exceeds that of LDL. The metabolism of chylomicron remnants and, hence, their accumulation in plasma, is governed by clearance of these particles by the liver, but the precise mechanisms involved remain unclear [ [2] Havel R.J. Chylomicron remnants: hepatic receptors and metabolism. Curr. Opin. Lipidol. 1995; 6: 312-316 Crossref PubMed Scopus (52) Google Scholar ]." @default.
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- W2028004022 date "2000-02-01" @default.
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- W2028004022 title "Postprandial lipaemia in familial hypercholesterolaemia: clinical and metabolic significance" @default.
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