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- W2028017990 abstract "The effect of systemically injected anti-hamster lymphocyte serum (ALS) on chemical carcinogenesis of the buccal pouch has been studied in thirty Syrian hamsters. In ten animals the right buccal pouch was painted with a 0.5 per cent solution of 9,10-dimethyl-1,2-benzanthracene (DMBA) in heavy mineral oil. Ten animals were painted with DMBA and also injected intraperitoneally with 0.45 ml. of ALS. The remaining ten animals served as untreated controls. There was a higher incidence of carcinoma in the ALSDMBA group and a suggestion of earlier tumor development. Histologically, the ALSDMBA group presented a consistent tumor pattern with more deep invasion and more anaplasticity than the control group. The pouches of the ALSDMBA group were more extensively involved in the development of neoplastic changes." @default.
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- W2028017990 date "1971-03-01" @default.
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- W2028017990 title "The effect of antilymphocyte serum on experimental hamster buccal pouch carcinogenesis" @default.
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- W2028017990 doi "https://doi.org/10.1016/0030-4220(71)90157-5" @default.
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