Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028043561> ?p ?o ?g. }
- W2028043561 endingPage "135" @default.
- W2028043561 startingPage "135" @default.
- W2028043561 abstract "In general, rats and mice have not been used in research on emesis because they do not vomit. However, emetogenic stimuli such as anticancer drugs, apomorphine, copper sulfate and rotation induced pica, a behavior characterized by eating nonfood substances such as kaolin, in rats. We also found that cisplatin induced pica in mice, but it was rather difficult to determine the exact kaolin consumption in this species. In this study, we prepared kaolin pellets mixed with carmine, a dye not absorbed in the gastrointestinal tract, and estimated kaolin consumption by determination of carmine excreted in feces. Cisplatin (5 mg/kg) caused a significant increase in kaolin consumption (saline: 0.15 +/- 0.08 g vs. cisplatin: 0.45 +/- 0.16 g) and pretreatment with the 5-HT3 receptor antagonist, ondansetron (2 mg/kg), suppressed the increased consumption (vehicle: 0.33 +/- 0.05 g vs. ondansetron: 0.13 +/- 0.04 g). These findings suggested that the exact kaolin consumption could be quantified by the determination of carmine in feces and that mice could be useful for studying emesis." @default.
- W2028043561 created "2016-06-24" @default.
- W2028043561 creator A5001306579 @default.
- W2028043561 creator A5028422211 @default.
- W2028043561 creator A5037128335 @default.
- W2028043561 creator A5075530194 @default.
- W2028043561 creator A5091806865 @default.
- W2028043561 date "2002-01-01" @default.
- W2028043561 modified "2023-10-16" @default.
- W2028043561 title "Pica in mice as a new model for the study of emesis" @default.
- W2028043561 doi "https://doi.org/10.1358/mf.2002.24.3.802297" @default.
- W2028043561 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12087874" @default.
- W2028043561 hasPublicationYear "2002" @default.
- W2028043561 type Work @default.
- W2028043561 sameAs 2028043561 @default.
- W2028043561 citedByCount "61" @default.
- W2028043561 countsByYear W20280435612012 @default.
- W2028043561 countsByYear W20280435612013 @default.
- W2028043561 countsByYear W20280435612014 @default.
- W2028043561 countsByYear W20280435612015 @default.
- W2028043561 countsByYear W20280435612016 @default.
- W2028043561 countsByYear W20280435612017 @default.
- W2028043561 countsByYear W20280435612018 @default.
- W2028043561 countsByYear W20280435612019 @default.
- W2028043561 countsByYear W20280435612020 @default.
- W2028043561 countsByYear W20280435612021 @default.
- W2028043561 countsByYear W20280435612022 @default.
- W2028043561 countsByYear W20280435612023 @default.
- W2028043561 crossrefType "journal-article" @default.
- W2028043561 hasAuthorship W2028043561A5001306579 @default.
- W2028043561 hasAuthorship W2028043561A5028422211 @default.
- W2028043561 hasAuthorship W2028043561A5037128335 @default.
- W2028043561 hasAuthorship W2028043561A5075530194 @default.
- W2028043561 hasAuthorship W2028043561A5091806865 @default.
- W2028043561 hasConcept C126322002 @default.
- W2028043561 hasConcept C136764020 @default.
- W2028043561 hasConcept C162324750 @default.
- W2028043561 hasConcept C170493617 @default.
- W2028043561 hasConcept C185592680 @default.
- W2028043561 hasConcept C2776622089 @default.
- W2028043561 hasConcept C2776694085 @default.
- W2028043561 hasConcept C2776885963 @default.
- W2028043561 hasConcept C2777170512 @default.
- W2028043561 hasConcept C2777397205 @default.
- W2028043561 hasConcept C2778239845 @default.
- W2028043561 hasConcept C2780512811 @default.
- W2028043561 hasConcept C2780852908 @default.
- W2028043561 hasConcept C2987526018 @default.
- W2028043561 hasConcept C41008148 @default.
- W2028043561 hasConcept C42219234 @default.
- W2028043561 hasConcept C48824518 @default.
- W2028043561 hasConcept C55493867 @default.
- W2028043561 hasConcept C61716771 @default.
- W2028043561 hasConcept C71924100 @default.
- W2028043561 hasConcept C86803240 @default.
- W2028043561 hasConcept C89423630 @default.
- W2028043561 hasConcept C98274493 @default.
- W2028043561 hasConceptScore W2028043561C126322002 @default.
- W2028043561 hasConceptScore W2028043561C136764020 @default.
- W2028043561 hasConceptScore W2028043561C162324750 @default.
- W2028043561 hasConceptScore W2028043561C170493617 @default.
- W2028043561 hasConceptScore W2028043561C185592680 @default.
- W2028043561 hasConceptScore W2028043561C2776622089 @default.
- W2028043561 hasConceptScore W2028043561C2776694085 @default.
- W2028043561 hasConceptScore W2028043561C2776885963 @default.
- W2028043561 hasConceptScore W2028043561C2777170512 @default.
- W2028043561 hasConceptScore W2028043561C2777397205 @default.
- W2028043561 hasConceptScore W2028043561C2778239845 @default.
- W2028043561 hasConceptScore W2028043561C2780512811 @default.
- W2028043561 hasConceptScore W2028043561C2780852908 @default.
- W2028043561 hasConceptScore W2028043561C2987526018 @default.
- W2028043561 hasConceptScore W2028043561C41008148 @default.
- W2028043561 hasConceptScore W2028043561C42219234 @default.
- W2028043561 hasConceptScore W2028043561C48824518 @default.
- W2028043561 hasConceptScore W2028043561C55493867 @default.
- W2028043561 hasConceptScore W2028043561C61716771 @default.
- W2028043561 hasConceptScore W2028043561C71924100 @default.
- W2028043561 hasConceptScore W2028043561C86803240 @default.
- W2028043561 hasConceptScore W2028043561C89423630 @default.
- W2028043561 hasConceptScore W2028043561C98274493 @default.
- W2028043561 hasIssue "3" @default.
- W2028043561 hasLocation W20280435611 @default.
- W2028043561 hasLocation W20280435612 @default.
- W2028043561 hasOpenAccess W2028043561 @default.
- W2028043561 hasPrimaryLocation W20280435611 @default.
- W2028043561 hasRelatedWork W1970005942 @default.
- W2028043561 hasRelatedWork W2183675838 @default.
- W2028043561 hasRelatedWork W2358286500 @default.
- W2028043561 hasRelatedWork W2417483213 @default.
- W2028043561 hasRelatedWork W2440670392 @default.
- W2028043561 hasRelatedWork W4230064089 @default.
- W2028043561 hasRelatedWork W4243605458 @default.
- W2028043561 hasRelatedWork W46470815 @default.
- W2028043561 hasRelatedWork W2397758540 @default.
- W2028043561 hasRelatedWork W2472148225 @default.
- W2028043561 hasVolume "24" @default.
- W2028043561 isParatext "false" @default.
- W2028043561 isRetracted "false" @default.