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- W2028049804 abstract "Conflicting results have been reported on the effect of oral contraceptives on antithrombin III levels. We measured antithrombin III by functional and immunologic assays on plasma and serum from women on oral contraceptives and from normal female controls. Plasma antithrombin III activity, measured by a heparin cofactor assay, was significantly decreased in women on oral contraceptives (79.8% ± 14.6 (1 S.D.)) compared to normal controls (101.5% ± 23.4) (p < .01). Plasma antithrombin III antigen was also decreased in women on oral contraceptives but the difference was not statistically significant (p > .05). Serum assays gave variable results. These studies support the conclusion that a true decrease in plasma antithrombin III occurs in women on oral contraceptives. For these studies we devised a modified heparin cofactor assay, which is accurate and inexpensive and does not require defibrinated plasma." @default.
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- W2028049804 date "1981-10-01" @default.
- W2028049804 modified "2023-09-26" @default.
- W2028049804 title "Effect of oral contraceptives on antithrombin III" @default.
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- W2028049804 doi "https://doi.org/10.1016/0049-3848(81)90027-x" @default.
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