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- W2028054891 abstract "The anorectic effects of ( + )-amphetamine, mephentermine, methylphenidate, amantα-dine, or fenfluramine were examined in animals pretreated intracisternally with either 6-hydroxydopamine or 5,7-dihydroxytryptamine. Destruction of brain dopamine systems antagonized the anorectic effect of ( +)-amphetamine and mephentermine, but did not block the anorectic effects of fenfluramine. Neither destruction of brain norepinephrine systems nor depletion of norepinephrine with the dopamine-β-hydroxylase inhibitor, U-14,624, antagonized the anorectic response to ( + )-amphetamine. While destruction of brain serotonin-containing systems did not alter the anorectic response to ( + )-amphetamine, it significantly enhanced the anorectic potency of fenfluramine." @default.
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- W2028054891 date "1975-10-01" @default.
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- W2028054891 title "The roles of monoamine neural systems in the anorexia induced by (+)-amphetamine and related compounds" @default.
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- W2028054891 doi "https://doi.org/10.1016/0028-3908(75)90096-9" @default.
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