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- W2028077196 abstract "Discussion and Gcneval ConclusionsThese results indicate that adenovirus type 2 infection may be established in the newborn Syrian hamster as a result of parenteral injection of a relatively high virus dose. Virus was rapidly absorbed from the injection site and disseminated via the circulation and detected in blood. liver, and kidney before a single virus replication cycle had occurred. Prefelential distribution to these organ is consistent with the magnitude of their blood supply (8).Replication had occurred in liver and kidney by 48 hr and the infectivity of these organs continued to increase through 144 hr, generally parallel with infectivity of serum. Since gross pathological changes and virus particles were found in these organs only and viral inclusions were found in liver cells only it is concluded that the major sites of viral replication were in cells of these organs. The viremia which occurred after replication had been established in these organs probably was a reflection of this however, vira..." @default.
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- W2028077196 title "A Generalized Infection of Newborn Hamsters with Type 2 Adenovirus" @default.
- W2028077196 doi "https://doi.org/10.3181/00379727-133-34538" @default.
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