FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028116003> ?p ?o ?g. }

• W2028116003 endingPage "698" @default.
• W2028116003 startingPage "687" @default.
• W2028116003 abstract "Background: Local ablative techniques such as selective internal radiation therapy (SIRT) have become the mainstay of treating hepatocellular carcinoma (HCC) in the bridging-to-transplant and palliative setting. We recently demonstrated that epithelial circulating tumor cells (CTCs) correlate to an unfavorable outcome. We wanted to scrutinize whether molecular markers detected in this specific CTC subgroup may also have clinical implications. Materials & methods: Mononuclear cells and CTCs were isolated from peripheral blood samples using density gradient centrifugation followed by depletion of hematopoietic and enrichment of epithelial (EpCAM + ) cells employing immunomagnetic beads. The mRNA expression of candidate markers was correlated with response to SIRT in 25 patients using quantitative real-time reverse-transcription PCR. Results: IGFBP1 mRNA expression levels were significantly correlated with time to progression in a Kaplan–Meier log rank test (p = 0.04; 0 vs 4 months) and receiver operating characteristic analysis demonstrated a potential use to predict patients with shortened time to progression (area under the curve: 0.8; 95% CI: 0.44–0.98; p = 0.03). Conclusion: The EpCAM fraction of CTCs may be useful to detect novel molecular markers to individualize treatment decision in patients with HCC." @default.
• W2028116003 created "2016-06-24" @default.
• W2028116003 creator A5032501532 @default.
• W2028116003 creator A5046522918 @default.
• W2028116003 creator A5052731204 @default.
• W2028116003 creator A5062978338 @default.
• W2028116003 creator A5063961467 @default.
• W2028116003 creator A5076135264 @default.
• W2028116003 creator A5087611420 @default.
• W2028116003 creator A5089575468 @default.
• W2028116003 date "2014-06-01" @default.
• W2028116003 modified "2023-09-25" @default.
• W2028116003 title "IGFBP1 in epithelial circulating tumor cells as a potential response marker to selective internal radiation therapy in hepatocellular carcinoma" @default.
• W2028116003 cites W144679933 @default.
• W2028116003 cites W1550300650 @default.
• W2028116003 cites W1964457754 @default.
• W2028116003 cites W1966672720 @default.
• W2028116003 cites W1986971722 @default.
• W2028116003 cites W1992463603 @default.
• W2028116003 cites W2004718750 @default.
• W2028116003 cites W2048346637 @default.
• W2028116003 cites W2049901759 @default.
• W2028116003 cites W2051364294 @default.
• W2028116003 cites W2052122154 @default.
• W2028116003 cites W2067532335 @default.
• W2028116003 cites W2074005829 @default.
• W2028116003 cites W2094351112 @default.
• W2028116003 cites W2101782801 @default.
• W2028116003 cites W2106787323 @default.
• W2028116003 cites W2111976640 @default.
• W2028116003 cites W2116483002 @default.
• W2028116003 cites W2118236274 @default.
• W2028116003 cites W2124474317 @default.
• W2028116003 cites W2126822099 @default.
• W2028116003 cites W2127342594 @default.
• W2028116003 cites W2139248078 @default.
• W2028116003 cites W2158714422 @default.
• W2028116003 cites W4243625103 @default.
• W2028116003 doi "https://doi.org/10.2217/bmm.14.23" @default.
• W2028116003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25123037" @default.
• W2028116003 hasPublicationYear "2014" @default.
• W2028116003 type Work @default.
• W2028116003 sameAs 2028116003 @default.
• W2028116003 citedByCount "10" @default.
• W2028116003 countsByYear W20281160032016 @default.
• W2028116003 countsByYear W20281160032017 @default.
• W2028116003 countsByYear W20281160032020 @default.
• W2028116003 countsByYear W20281160032021 @default.
• W2028116003 crossrefType "journal-article" @default.
• W2028116003 hasAuthorship W2028116003A5032501532 @default.
• W2028116003 hasAuthorship W2028116003A5046522918 @default.
• W2028116003 hasAuthorship W2028116003A5052731204 @default.
• W2028116003 hasAuthorship W2028116003A5062978338 @default.
• W2028116003 hasAuthorship W2028116003A5063961467 @default.
• W2028116003 hasAuthorship W2028116003A5076135264 @default.
• W2028116003 hasAuthorship W2028116003A5087611420 @default.
• W2028116003 hasAuthorship W2028116003A5089575468 @default.
• W2028116003 hasConcept C109159458 @default.
• W2028116003 hasConcept C121608353 @default.
• W2028116003 hasConcept C126322002 @default.
• W2028116003 hasConcept C137061746 @default.
• W2028116003 hasConcept C143998085 @default.
• W2028116003 hasConcept C153911025 @default.
• W2028116003 hasConcept C202751555 @default.
• W2028116003 hasConcept C2776677690 @default.
• W2028116003 hasConcept C2778019345 @default.
• W2028116003 hasConcept C2779013556 @default.
• W2028116003 hasConcept C2779256057 @default.
• W2028116003 hasConcept C2781053203 @default.
• W2028116003 hasConcept C28328180 @default.
• W2028116003 hasConcept C502942594 @default.
• W2028116003 hasConcept C54355233 @default.
• W2028116003 hasConcept C55493867 @default.
• W2028116003 hasConcept C61238886 @default.
• W2028116003 hasConcept C71924100 @default.
• W2028116003 hasConcept C86803240 @default.
• W2028116003 hasConceptScore W2028116003C109159458 @default.
• W2028116003 hasConceptScore W2028116003C121608353 @default.
• W2028116003 hasConceptScore W2028116003C126322002 @default.
• W2028116003 hasConceptScore W2028116003C137061746 @default.
• W2028116003 hasConceptScore W2028116003C143998085 @default.
• W2028116003 hasConceptScore W2028116003C153911025 @default.
• W2028116003 hasConceptScore W2028116003C202751555 @default.
• W2028116003 hasConceptScore W2028116003C2776677690 @default.
• W2028116003 hasConceptScore W2028116003C2778019345 @default.
• W2028116003 hasConceptScore W2028116003C2779013556 @default.
• W2028116003 hasConceptScore W2028116003C2779256057 @default.
• W2028116003 hasConceptScore W2028116003C2781053203 @default.
• W2028116003 hasConceptScore W2028116003C28328180 @default.
• W2028116003 hasConceptScore W2028116003C502942594 @default.
• W2028116003 hasConceptScore W2028116003C54355233 @default.
• W2028116003 hasConceptScore W2028116003C55493867 @default.
• W2028116003 hasConceptScore W2028116003C61238886 @default.
• W2028116003 hasConceptScore W2028116003C71924100 @default.
• W2028116003 hasConceptScore W2028116003C86803240 @default.
• W2028116003 hasIssue "5" @default.
• W2028116003 hasLocation W20281160031 @default.
• W2028116003 hasLocation W20281160032 @default.

• next