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- W2028134073 abstract "In this paper a novel application of solid acid catalysts in the chemoselective Friedel–Crafts (FC) alkylation of indoles is reported. The optimal protocol allows highly functionalised indolyl compounds to be synthesised in excellent yields through conjugate addition of indoles with α,β-unsaturated ketones and nitro compounds. Finally, the use of commercial Amberlyst-15 as the heterogeneous catalyst for highly atom efficient continuous and semicontinuous Friedel–Crafts processes is described." @default.
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- W2028134073 date "2004-04-01" @default.
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- W2028134073 title "Solid Acid-Catalysed Michael-Type Conjugate Addition of Indoles to Electron-Poor CC Bonds: Towards High Atom Economical Semicontinuous Processes" @default.
- W2028134073 doi "https://doi.org/10.1002/adsc.200303213" @default.
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