FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028171657> ?p ?o ?g. }

• W2028171657 endingPage "A73" @default.
• W2028171657 startingPage "A72.3" @default.
• W2028171657 abstract "<h3>Introduction</h3> Faecal calprotectin is a sensitive measure of neutrophilic intestinal inflammation; use in gastroenterological screening has been proposed, reducing invasive and costly lower gastrointestinal (GI) endoscopy, particularly when functional disorders are suspected [1]. We reviewed all faecal calprotectin results and available patient records over a six month period to determine whether a normal faecal calprotectin resulted in subsequent avoidance of lower GI endoscopy. <h3>Methods</h3> The paper and/or electronic medical records for patients with calprotectin requests over a 6 month period were accessed and reviewed by a Specialty Trainee in gastroenterology at Lancashire Teaching Hospitals NHS Foundation Trust. Demographic data, symptoms, and recent or subsequent lower GI endoscopy were recorded. Endoscopy was considered ‘spared’ if the diagnosis was anticipated to be functional and a normal faecal calprotectin resulted in avoidance of lower GI endoscopy; or in patients with known inflammatory bowel disease (IBD) where the notes intimated a normal calprotectin would result in avoidance of further endoscopy. <h3>Results</h3> 122 patients (73 female, mean age 41yrs, range 16–89yrs) had faecal calprotectin requests sent from the Royal Preston Hospital and Chorley and South Ribble Hospital. 4 samples were not received or processed. 90.2% were outpatient requests, and the most common indications were loose stools (54.1%) and abdominal pain (28.7%). 45 samples (36.9%) had a raised calprotectin (≥51μg/g), of which 20 patients had known IBD. In those with a normal calprotectin (n = 73), 56 had an unclear diagnosis of which 4 (7.1%) eventually went on to have lower GI endoscopy with no major findings, and 20 patients (35.7%) had previously undergone lower GI endoscopy. In 13 patients there were insufficient records available to be able to comment. According to the criteria mentioned 35 patients were spared lower GI endoscopy within the 6 month period. <h3>Conclusion</h3> Over a 6 month period 35 lower GI endoscopies were avoided representing both a reduction in patient exposure to the risks of endoscopy and a significant financial saving. Our results suggest that faecal calprotectin is a valuable and cost effective resource in helping to exclude significant organic pathology in selected patients given its proven high negative predictive value in excluding gastrointestinal inflammation [2]. <h3>Disclosure of Interest</h3> None Declared <h3>References</h3> Licata A <i>et al.</i> J Clin Gastroenterol. 2012; 46:504–8. Meucci G <i>et al.</i><i></i> Dig Liver Dis. 2010; 42:191–5" @default.
• W2028171657 created "2016-06-24" @default.
• W2028171657 creator A5018512571 @default.
• W2028171657 creator A5061194559 @default.
• W2028171657 creator A5076673859 @default.
• W2028171657 creator A5088139881 @default.
• W2028171657 date "2013-06-01" @default.
• W2028171657 modified "2023-09-27" @default.
• W2028171657 title "PTU-069 The Effect of Faecal Calprotectin on the use of Colonoscopy at Lancashire Teaching Hospitals NHS Foundation Trust" @default.
• W2028171657 doi "https://doi.org/10.1136/gutjnl-2013-304907.161" @default.
• W2028171657 hasPublicationYear "2013" @default.
• W2028171657 type Work @default.
• W2028171657 sameAs 2028171657 @default.
• W2028171657 citedByCount "0" @default.
• W2028171657 crossrefType "journal-article" @default.
• W2028171657 hasAuthorship W2028171657A5018512571 @default.
• W2028171657 hasAuthorship W2028171657A5061194559 @default.
• W2028171657 hasAuthorship W2028171657A5076673859 @default.
• W2028171657 hasAuthorship W2028171657A5088139881 @default.
• W2028171657 hasBestOaLocation W20281716571 @default.
• W2028171657 hasConcept C121608353 @default.
• W2028171657 hasConcept C126322002 @default.
• W2028171657 hasConcept C142724271 @default.
• W2028171657 hasConcept C195910791 @default.
• W2028171657 hasConcept C20387591 @default.
• W2028171657 hasConcept C2778260677 @default.
• W2028171657 hasConcept C2778292693 @default.
• W2028171657 hasConcept C2778435480 @default.
• W2028171657 hasConcept C2778451229 @default.
• W2028171657 hasConcept C2779008522 @default.
• W2028171657 hasConcept C2779134260 @default.
• W2028171657 hasConcept C2780955771 @default.
• W2028171657 hasConcept C3020110884 @default.
• W2028171657 hasConcept C526805850 @default.
• W2028171657 hasConcept C61434518 @default.
• W2028171657 hasConcept C71924100 @default.
• W2028171657 hasConcept C90924648 @default.
• W2028171657 hasConceptScore W2028171657C121608353 @default.
• W2028171657 hasConceptScore W2028171657C126322002 @default.
• W2028171657 hasConceptScore W2028171657C142724271 @default.
• W2028171657 hasConceptScore W2028171657C195910791 @default.
• W2028171657 hasConceptScore W2028171657C20387591 @default.
• W2028171657 hasConceptScore W2028171657C2778260677 @default.
• W2028171657 hasConceptScore W2028171657C2778292693 @default.
• W2028171657 hasConceptScore W2028171657C2778435480 @default.
• W2028171657 hasConceptScore W2028171657C2778451229 @default.
• W2028171657 hasConceptScore W2028171657C2779008522 @default.
• W2028171657 hasConceptScore W2028171657C2779134260 @default.
• W2028171657 hasConceptScore W2028171657C2780955771 @default.
• W2028171657 hasConceptScore W2028171657C3020110884 @default.
• W2028171657 hasConceptScore W2028171657C526805850 @default.
• W2028171657 hasConceptScore W2028171657C61434518 @default.
• W2028171657 hasConceptScore W2028171657C71924100 @default.
• W2028171657 hasConceptScore W2028171657C90924648 @default.
• W2028171657 hasIssue "Suppl 1" @default.
• W2028171657 hasLocation W20281716571 @default.
• W2028171657 hasOpenAccess W2028171657 @default.
• W2028171657 hasPrimaryLocation W20281716571 @default.
• W2028171657 hasRelatedWork W1975032444 @default.
• W2028171657 hasRelatedWork W2024216943 @default.
• W2028171657 hasRelatedWork W2024875867 @default.
• W2028171657 hasRelatedWork W2028171657 @default.
• W2028171657 hasRelatedWork W2077443323 @default.
• W2028171657 hasRelatedWork W2102384908 @default.
• W2028171657 hasRelatedWork W2408063345 @default.
• W2028171657 hasRelatedWork W2415231086 @default.
• W2028171657 hasRelatedWork W2785489657 @default.
• W2028171657 hasRelatedWork W4212847486 @default.
• W2028171657 hasVolume "62" @default.
• W2028171657 isParatext "false" @default.
• W2028171657 isRetracted "false" @default.
• W2028171657 magId "2028171657" @default.
• W2028171657 workType "article" @default.