Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028180869> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2028180869 endingPage "211" @default.
- W2028180869 startingPage "207" @default.
- W2028180869 abstract "We have studied the effect of ramipril (10 mg/kg daily by gastric gavage) on the development of neointima 2 and 14 days after injury to rat aorta with a balloon catheter. In treated animals, there was no significant inhibition of the early mitotic reaction after injury (synthesis of DNA. as reflected by aortic thymidine incorporation on the second day): the mean (95% confidence interval) was 3.553 (892) in the control group vs. 2.853 disintegrations/min/μg of DNA (555) in the treated group. 2p > 0.15. However, ramipril decreased the amount of neointima formed 14 days after injury, as characterized by (a) a highly significant decrease of the intima to intima + media areas ratio [21.1 (2.4) vs. 13.7% (2.2), 2p < 10−4]; (b) a significant decrease of intima-media wet weight [35.4 (1.0) vs. 30.9 mg (0.9), 2p < 0.005]; and (c) without any significant effect on intima-media DNA content [96.3 (7.9) vs. 91.7 μg (5.7). 2p > 0.3]. These observations suggest that angiotensin converting enzyme inhibitors may not act mainly through an inhibition of smooth muscle cell proliferation. Other effects, such as inhibition of migration, hypertrophy, and matrix synthesis, should also be considered." @default.
- W2028180869 created "2016-06-24" @default.
- W2028180869 creator A5023581472 @default.
- W2028180869 creator A5028555797 @default.
- W2028180869 creator A5068134101 @default.
- W2028180869 creator A5074883217 @default.
- W2028180869 date "1991-08-01" @default.
- W2028180869 modified "2023-09-27" @default.
- W2028180869 title "Effect of Ramipril, an Inhibitor of Angiotensin Converting Enzyme, on the Response of Rat Thoracic Aorta to Injury with a Balloon Catheter" @default.
- W2028180869 doi "https://doi.org/10.1097/00005344-199108000-00005" @default.
- W2028180869 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1717780" @default.
- W2028180869 hasPublicationYear "1991" @default.
- W2028180869 type Work @default.
- W2028180869 sameAs 2028180869 @default.
- W2028180869 citedByCount "45" @default.
- W2028180869 crossrefType "journal-article" @default.
- W2028180869 hasAuthorship W2028180869A5023581472 @default.
- W2028180869 hasAuthorship W2028180869A5028555797 @default.
- W2028180869 hasAuthorship W2028180869A5068134101 @default.
- W2028180869 hasAuthorship W2028180869A5074883217 @default.
- W2028180869 hasBestOaLocation W20281808691 @default.
- W2028180869 hasConcept C126322002 @default.
- W2028180869 hasConcept C134018914 @default.
- W2028180869 hasConcept C139059822 @default.
- W2028180869 hasConcept C185592680 @default.
- W2028180869 hasConcept C27016395 @default.
- W2028180869 hasConcept C2777339539 @default.
- W2028180869 hasConcept C2778283817 @default.
- W2028180869 hasConcept C2778583881 @default.
- W2028180869 hasConcept C2779611605 @default.
- W2028180869 hasConcept C2779888176 @default.
- W2028180869 hasConcept C2779980429 @default.
- W2028180869 hasConcept C2993470428 @default.
- W2028180869 hasConcept C71924100 @default.
- W2028180869 hasConcept C84393581 @default.
- W2028180869 hasConceptScore W2028180869C126322002 @default.
- W2028180869 hasConceptScore W2028180869C134018914 @default.
- W2028180869 hasConceptScore W2028180869C139059822 @default.
- W2028180869 hasConceptScore W2028180869C185592680 @default.
- W2028180869 hasConceptScore W2028180869C27016395 @default.
- W2028180869 hasConceptScore W2028180869C2777339539 @default.
- W2028180869 hasConceptScore W2028180869C2778283817 @default.
- W2028180869 hasConceptScore W2028180869C2778583881 @default.
- W2028180869 hasConceptScore W2028180869C2779611605 @default.
- W2028180869 hasConceptScore W2028180869C2779888176 @default.
- W2028180869 hasConceptScore W2028180869C2779980429 @default.
- W2028180869 hasConceptScore W2028180869C2993470428 @default.
- W2028180869 hasConceptScore W2028180869C71924100 @default.
- W2028180869 hasConceptScore W2028180869C84393581 @default.
- W2028180869 hasIssue "2" @default.
- W2028180869 hasLocation W20281808691 @default.
- W2028180869 hasLocation W20281808692 @default.
- W2028180869 hasLocation W20281808693 @default.
- W2028180869 hasOpenAccess W2028180869 @default.
- W2028180869 hasPrimaryLocation W20281808691 @default.
- W2028180869 hasRelatedWork W1964723030 @default.
- W2028180869 hasRelatedWork W1992705822 @default.
- W2028180869 hasRelatedWork W2005927873 @default.
- W2028180869 hasRelatedWork W2136191582 @default.
- W2028180869 hasRelatedWork W2353484226 @default.
- W2028180869 hasRelatedWork W2379694518 @default.
- W2028180869 hasRelatedWork W2386733398 @default.
- W2028180869 hasRelatedWork W2396397547 @default.
- W2028180869 hasRelatedWork W2748952813 @default.
- W2028180869 hasRelatedWork W3143383587 @default.
- W2028180869 hasVolume "18" @default.
- W2028180869 isParatext "false" @default.
- W2028180869 isRetracted "false" @default.
- W2028180869 magId "2028180869" @default.
- W2028180869 workType "article" @default.