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- W2028185849 abstract "Study population: 30 pairs of male children (30 exposed [E] and 30 non-exposed [NE]) matched for age, height, socio-economic level and non-smoking mothers. All boys had lived and attended to school in their own area for all his life. Study variables: forced vital capacity (FVC), forced expiratory volume 1st sec (FEV1), FEV1/FVC ratio, mean expiratory flows at 25% (MEF25), 50% (MEF50) and 75% (MEF75) of expired volume, and mean forced expiratory flow during the middle half of FVC (FEF). Spirometry was recorded before and after (10') the administration of fenoterol (150 μg). A positive bronchodilating test (+BD) was defined as a 10% increment on FVC or a 12% increment in PEFR. Differences prior to fenoterol: FEV1/FVC (94.2±4.9 [NE], 97.5±3.8 [E]; p=0.007), FEF (2.71±0.57 [NE], 3.1±0.85 [E]; p=0.042). Differences after fenoterol: FEV1/FVC (94.2±4.9[NE], 97.5±3.8[E]; p=0.007), MEF25 (1.74±0.47 [NE], 2.08±0.64 [E]; p=0.022), MEF50 (3.12±0.56 [NE], 3.57±0.83 [E]; p = 0.017), FEF (2.79±0.49 [NE], 3.16±0.83 [E], p=0.045). The risk of +BD for non-exposed boys was RR = 1.32 (95% confidence limits 0.96 < RR < 1.8). Conclusions: Exposed boys had a normal spirometry. Non exposed boys had more +BD, suggesting more “active” airways of a shift of families from one area to another more than 10 yr ago." @default.
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- W2028185849 date "1994-07-01" @default.
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- W2028185849 title "320 PULMONARY FUNCTION IN HEALTHY BOYS 11 YEARS OLD AND OUTDOOR AIR POLLUTION (S02). A RETROSPECTIVE COHORT STUDY" @default.
- W2028185849 doi "https://doi.org/10.1203/00006450-199407000-00320" @default.
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