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- W2028202589 abstract "By means of a modified revolving-cage test, the effect of methylphenidate as compared with other centrally acting drugs has been studied in rats subjected to forced muscular exercise. Methylphenidate increased the performance of trained animals while amphetamine and ibogaine were inefficient. The running ability of untrained rats was also improved by the administration of methylphenidate. All the central nervous depressants tested (e.g., meprobamate, chlorpromazine, and perphenazine) diminished the performance of animals at the dose utilized. This depressive action was counteracted by methylphenidate. Methylphenidate only antagonized perphenazine when the two agents were given in combination, before the animals were exposed to forced muscular exercise." @default.
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- W2028202589 date "1959-03-01" @default.
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- W2028202589 title "EFFECT OF CENTRALLY ACTING DRUGS UPON MUSCULAR EXERCISE IN RATS" @default.
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- W2028202589 doi "https://doi.org/10.1139/o59-043" @default.
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