FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028224074> ?p ?o ?g. }

• W2028224074 endingPage "1923" @default.
• W2028224074 startingPage "1914" @default.
• W2028224074 abstract "A retrospective analysis of pooled data from twelve placebo-controlled trials was conducted to characterise the efficacy and safety of tadalafil for the treatment of erectile dysfunction in men with diabetes compared with that in men without diabetes. Patients were randomly allocated to tadalafil 10 mg, 20 mg, or placebo, taken as needed for 12 weeks. The study population comprised 637 men with diabetes (mean age 57 years) and 1681 men without diabetes (mean age 56 years). At baseline, patients with diabetes had more severe erectile dysfunction than patients without diabetes, with mean International Index of Erectile Function (IIEF) erectile function domain scores of 12.6 and 15.0 respectively (p<0.001). Compared with placebo, tadalafil 10 mg and 20 mg improved all primary efficacy outcomes in both patient groups (p<0.001). Men with diabetes receiving tadalafil 20 mg experienced a mean improvement of 7.4 in their IIEF erectile function domain score against baseline versus 0.9 for placebo (p<0.001). This group reported on average that 53% of their attempts at intercourse were successful, compared with 22% for placebo (p<0.001 for the change from baseline). Baseline IIEF erectile function domain scores correlated inversely with baseline HbA1c levels. The responses to tadalafil were similar regardless of levels of baseline glycaemic control, diabetic therapy received, or previous use of sildenafil. Despite more severe baseline erectile dysfunction in men with diabetes, tadalafil was efficacious and well tolerated in this population. As reported for other phosphodiesterase 5 inhibitors, the response to tadalafil was slightly lower in men with diabetes than in men without diabetes." @default.
• W2028224074 created "2016-06-24" @default.
• W2028224074 creator A5007493755 @default.
• W2028224074 creator A5034671525 @default.
• W2028224074 creator A5071651050 @default.
• W2028224074 creator A5086333788 @default.
• W2028224074 date "2004-11-01" @default.
• W2028224074 modified "2023-10-17" @default.
• W2028224074 title "Impact of diabetes mellitus on the severity of erectile dysfunction and response to treatment: analysis of data from tadalafil clinical trials" @default.
• W2028224074 cites W1557695823 @default.
• W2028224074 cites W1965926180 @default.
• W2028224074 cites W1970134738 @default.
• W2028224074 cites W1993387626 @default.
• W2028224074 cites W1994574205 @default.
• W2028224074 cites W2002717704 @default.
• W2028224074 cites W2009639166 @default.
• W2028224074 cites W2019666885 @default.
• W2028224074 cites W2025002838 @default.
• W2028224074 cites W2052518051 @default.
• W2028224074 cites W2056147576 @default.
• W2028224074 cites W2061747153 @default.
• W2028224074 cites W2062907730 @default.
• W2028224074 cites W2063746422 @default.
• W2028224074 cites W2076357493 @default.
• W2028224074 cites W2086240335 @default.
• W2028224074 cites W2089736652 @default.
• W2028224074 cites W2099719839 @default.
• W2028224074 cites W2106776242 @default.
• W2028224074 cites W2106893238 @default.
• W2028224074 cites W2121939064 @default.
• W2028224074 cites W2122948438 @default.
• W2028224074 cites W2138798974 @default.
• W2028224074 cites W2146655079 @default.
• W2028224074 cites W2156867396 @default.
• W2028224074 cites W2158368439 @default.
• W2028224074 cites W2160324165 @default.
• W2028224074 cites W2170259285 @default.
• W2028224074 cites W2195988565 @default.
• W2028224074 cites W22857079 @default.
• W2028224074 cites W2297358297 @default.
• W2028224074 cites W2406062456 @default.
• W2028224074 doi "https://doi.org/10.1007/s00125-004-1549-6" @default.
• W2028224074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15599697" @default.
• W2028224074 hasPublicationYear "2004" @default.
• W2028224074 type Work @default.
• W2028224074 sameAs 2028224074 @default.
• W2028224074 citedByCount "137" @default.
• W2028224074 countsByYear W20282240742012 @default.
• W2028224074 countsByYear W20282240742013 @default.
• W2028224074 countsByYear W20282240742014 @default.
• W2028224074 countsByYear W20282240742015 @default.
• W2028224074 countsByYear W20282240742016 @default.
• W2028224074 countsByYear W20282240742017 @default.
• W2028224074 countsByYear W20282240742018 @default.
• W2028224074 countsByYear W20282240742019 @default.
• W2028224074 countsByYear W20282240742020 @default.
• W2028224074 countsByYear W20282240742021 @default.
• W2028224074 countsByYear W20282240742022 @default.
• W2028224074 crossrefType "journal-article" @default.
• W2028224074 hasAuthorship W2028224074A5007493755 @default.
• W2028224074 hasAuthorship W2028224074A5034671525 @default.
• W2028224074 hasAuthorship W2028224074A5071651050 @default.
• W2028224074 hasAuthorship W2028224074A5086333788 @default.
• W2028224074 hasBestOaLocation W20282240741 @default.
• W2028224074 hasConcept C126322002 @default.
• W2028224074 hasConcept C126894567 @default.
• W2028224074 hasConcept C134018914 @default.
• W2028224074 hasConcept C142724271 @default.
• W2028224074 hasConcept C204787440 @default.
• W2028224074 hasConcept C27081682 @default.
• W2028224074 hasConcept C2779929075 @default.
• W2028224074 hasConcept C2780816001 @default.
• W2028224074 hasConcept C2908647359 @default.
• W2028224074 hasConcept C555293320 @default.
• W2028224074 hasConcept C71924100 @default.
• W2028224074 hasConcept C74534348 @default.
• W2028224074 hasConcept C99454951 @default.
• W2028224074 hasConceptScore W2028224074C126322002 @default.
• W2028224074 hasConceptScore W2028224074C126894567 @default.
• W2028224074 hasConceptScore W2028224074C134018914 @default.
• W2028224074 hasConceptScore W2028224074C142724271 @default.
• W2028224074 hasConceptScore W2028224074C204787440 @default.
• W2028224074 hasConceptScore W2028224074C27081682 @default.
• W2028224074 hasConceptScore W2028224074C2779929075 @default.
• W2028224074 hasConceptScore W2028224074C2780816001 @default.
• W2028224074 hasConceptScore W2028224074C2908647359 @default.
• W2028224074 hasConceptScore W2028224074C555293320 @default.
• W2028224074 hasConceptScore W2028224074C71924100 @default.
• W2028224074 hasConceptScore W2028224074C74534348 @default.
• W2028224074 hasConceptScore W2028224074C99454951 @default.
• W2028224074 hasIssue "11" @default.
• W2028224074 hasLocation W20282240741 @default.
• W2028224074 hasLocation W20282240742 @default.
• W2028224074 hasOpenAccess W2028224074 @default.
• W2028224074 hasPrimaryLocation W20282240741 @default.
• W2028224074 hasRelatedWork W1570577237 @default.
• W2028224074 hasRelatedWork W1898711703 @default.
• W2028224074 hasRelatedWork W1999638102 @default.

• next