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- W2028245871 abstract "Sugar parts play important roles in recognizing molecules on the cell membranes. We successfully produced sugar-type micellar surfactants, lactonoalkylamide (LacCn), for the first time. Spherical vesicles, three-component hybrid liposomes, were obtained after the sonication of the mixture of L-alpha-dimyristoyl-phosphatidylcholine (DMPC), Tween 20 and LacCn (DMPC:Tween 20:LacCn=65:7:28). It is noteworthy that high inhibitory effects of the three-component hybrid liposomes composed of DMPC, Tween 20, and LacCn (DMPC:Tween 20:LacCn=65:7:28) on the growth of glioma (U251) and lung adenocarcinoma (RERF-LC-OK) cells were attained in vitro without any drug, although no significant inhibitory effects of any individual component (DMPC, Tween 20, LacCn) or the two-component hybrid liposomes of DMPC and Tween 20 on the growth of tumor cells examined were obtained." @default.
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- W2028245871 date "2002-01-01" @default.
- W2028245871 modified "2023-10-16" @default.
- W2028245871 title "Remarkably Enhanced Inhibitory Effects of Three-Component Hybrid Liposomes Including Sugar Surfactants on the Growth of Lung Carcinoma Cells." @default.
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- W2028245871 doi "https://doi.org/10.1248/cpb.50.563" @default.
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