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- W2028291025 abstract "Diabetic macular edema is the most common cause of visual impairment among diabetic patients. VEGF plays a major role in the pathogenesis of retinal edema in this context, as it induces angiogenesis and increases the permeability of retinal vessels. Inhibiting therapies are being studied, and ranibizumab – a recombinant humanized antibody fragment – has been approved for intravitreal use. Ranibizumab has been shown to improve functional and anatomical outcomes at 24 months, according to recent studies that compared it with standard focal/grid photocoagulation treatment, however, longer follow-up is needed to assess how this improvement is maintained over time. Guidelines for scheduled visits and retreatment have to be established to guarantee maximum effectiveness." @default.
- W2028291025 created "2016-06-24" @default.
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- W2028291025 date "2012-04-01" @default.
- W2028291025 modified "2023-10-18" @default.
- W2028291025 title "Ranibizumab for the treatment of visual impairment due to diabetic macular edema: evidence from recent clinical trials" @default.
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- W2028291025 doi "https://doi.org/10.4155/cli.12.15" @default.
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