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- W2028292085 abstract "Frequent co-activation of inputs resulting in a selective increase in their efficacy has long been associated with various learning phenomena but it is increasingly being invoked as an explanation for the ontogenetic refinement of neuronal response properties. The actual structure of the young nervous system could be changed by the activity it carries if, for example, two sets of terminals with frequently correlated potentials were reinforced at the expense of other terminals which might fire with equal frequency but in a non-coordinated pattern1.9.10. A recent paper by Udin11 on the inter-tectal visual projections of Xenopus provides very interesting evidence supporting this hypothesis. Udin presents a quantitative anatomical analysis demonstrating quite dramatic changes in the trajectories of axons which carry information about the binocular visual field between the two lobes of the optic tectum. This pathway is one where earlier physiological studies have correlated experimentally induced alterations in the frequency of co-activating two inputs with pronounced changes in the pattern with which they appear to project to their common target area." @default.
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- W2028292085 date "1983-01-01" @default.
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- W2028292085 title "Convergent activity patterns: can they alter axon trajectories?" @default.
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- W2028292085 doi "https://doi.org/10.1016/0166-2236(83)90212-6" @default.
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