FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028294443> ?p ?o ?g. }

• W2028294443 endingPage "882" @default.
• W2028294443 startingPage "873" @default.
• W2028294443 abstract "The induction of heat shock proteins in the myocardium has been suggested as a possible intervention to allow for enhanced cardioprotection. We have postulated that a brief period of retrograde hyperthermic perfusion would be sufficient to induce Hsp 70 mRNA and protein accumulation. To investigate this hypothesis, rat hearts (n = 45) were perfused at 37 degrees C for 30 min, then perfused for 15 min at 42 degrees C, and allowed to recover at 37 degrees C for 120 min. Control hearts (n = 23) were perfused at 37 degrees C continuously. Northern analysis indicated that in hearts treated with a brief period of retrograde hyperthermic perfusion Hsp 70 mRNA levels were increased 2.85 +/- 0.02-fold (P < 0.01) by 10 min, 4.88 +/- 0.94-fold (P < 0.01) by 15 min, 9.19 +/- 0.62-fold (P < 0.001) by 30 min, 9.4 +/- 0.52-fold (P < 0.001) by 60 min, 9.45 +/- 0.57-fold (P < 0.001) by 90 min and 9.66 +/- 0.99-fold (P < 0.001) by 120 min of normothermic recovery as compared to control hearts. Western analysis revealed that the heat inducible Hsp 72 kDa protein was increased 2.37 +/- 0.45-fold (P < 0.01) at 60 min, 2.53 +/- 0.25-fold (P < 0.01) at 90 min, and 2.7 +/- 0.6&-fold (P < 0.01) at 120 min when compared to control hearts. Our results indicate that the induction of the heat shock protein Hsp 70 can be rapidly achieved through retrograde hyperthermic perfusion of the myocardium." @default.
• W2028294443 created "2016-06-24" @default.
• W2028294443 creator A5008795581 @default.
• W2028294443 creator A5017115516 @default.
• W2028294443 creator A5029815474 @default.
• W2028294443 creator A5088028014 @default.
• W2028294443 creator A5091553412 @default.
• W2028294443 date "1995-03-01" @default.
• W2028294443 modified "2023-09-23" @default.
• W2028294443 title "The rapid expression of myocardial Hsp 70 mRNA and the heat shock 70 kDa protein can be achieved after only a brief period of retrograde hyperthermic perfusion" @default.
• W2028294443 cites W1523329627 @default.
• W2028294443 cites W1526510631 @default.
• W2028294443 cites W1548985056 @default.
• W2028294443 cites W1601634511 @default.
• W2028294443 cites W1775749144 @default.
• W2028294443 cites W1964301211 @default.
• W2028294443 cites W1989093194 @default.
• W2028294443 cites W1993141521 @default.
• W2028294443 cites W2008369719 @default.
• W2028294443 cites W2009410787 @default.
• W2028294443 cites W2011836510 @default.
• W2028294443 cites W2014669590 @default.
• W2028294443 cites W2020377054 @default.
• W2028294443 cites W2044531463 @default.
• W2028294443 cites W2055533988 @default.
• W2028294443 cites W2060071007 @default.
• W2028294443 cites W2063450941 @default.
• W2028294443 cites W2067708969 @default.
• W2028294443 cites W2079321385 @default.
• W2028294443 cites W2082365607 @default.
• W2028294443 cites W2083553869 @default.
• W2028294443 cites W2085231390 @default.
• W2028294443 cites W2134812217 @default.
• W2028294443 cites W2144634347 @default.
• W2028294443 cites W2165113979 @default.
• W2028294443 cites W2319916283 @default.
• W2028294443 cites W2405834129 @default.
• W2028294443 doi "https://doi.org/10.1016/0022-2828(95)90037-3" @default.
• W2028294443 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7602605" @default.
• W2028294443 hasPublicationYear "1995" @default.
• W2028294443 type Work @default.
• W2028294443 sameAs 2028294443 @default.
• W2028294443 citedByCount "17" @default.
• W2028294443 crossrefType "journal-article" @default.
• W2028294443 hasAuthorship W2028294443A5008795581 @default.
• W2028294443 hasAuthorship W2028294443A5017115516 @default.
• W2028294443 hasAuthorship W2028294443A5029815474 @default.
• W2028294443 hasAuthorship W2028294443A5088028014 @default.
• W2028294443 hasAuthorship W2028294443A5091553412 @default.
• W2028294443 hasConcept C104317684 @default.
• W2028294443 hasConcept C105580179 @default.
• W2028294443 hasConcept C126322002 @default.
• W2028294443 hasConcept C134018914 @default.
• W2028294443 hasConcept C146957229 @default.
• W2028294443 hasConcept C153911025 @default.
• W2028294443 hasConcept C16685009 @default.
• W2028294443 hasConcept C185592680 @default.
• W2028294443 hasConcept C205260736 @default.
• W2028294443 hasConcept C2779676291 @default.
• W2028294443 hasConcept C2781300812 @default.
• W2028294443 hasConcept C500558357 @default.
• W2028294443 hasConcept C55493867 @default.
• W2028294443 hasConcept C71924100 @default.
• W2028294443 hasConcept C86803240 @default.
• W2028294443 hasConceptScore W2028294443C104317684 @default.
• W2028294443 hasConceptScore W2028294443C105580179 @default.
• W2028294443 hasConceptScore W2028294443C126322002 @default.
• W2028294443 hasConceptScore W2028294443C134018914 @default.
• W2028294443 hasConceptScore W2028294443C146957229 @default.
• W2028294443 hasConceptScore W2028294443C153911025 @default.
• W2028294443 hasConceptScore W2028294443C16685009 @default.
• W2028294443 hasConceptScore W2028294443C185592680 @default.
• W2028294443 hasConceptScore W2028294443C205260736 @default.
• W2028294443 hasConceptScore W2028294443C2779676291 @default.
• W2028294443 hasConceptScore W2028294443C2781300812 @default.
• W2028294443 hasConceptScore W2028294443C500558357 @default.
• W2028294443 hasConceptScore W2028294443C55493867 @default.
• W2028294443 hasConceptScore W2028294443C71924100 @default.
• W2028294443 hasConceptScore W2028294443C86803240 @default.
• W2028294443 hasIssue "3" @default.
• W2028294443 hasLocation W20282944431 @default.
• W2028294443 hasLocation W20282944432 @default.
• W2028294443 hasOpenAccess W2028294443 @default.
• W2028294443 hasPrimaryLocation W20282944431 @default.
• W2028294443 hasRelatedWork W1964925713 @default.
• W2028294443 hasRelatedWork W1978332820 @default.
• W2028294443 hasRelatedWork W1980194808 @default.
• W2028294443 hasRelatedWork W1989634017 @default.
• W2028294443 hasRelatedWork W2032183296 @default.
• W2028294443 hasRelatedWork W2085474331 @default.
• W2028294443 hasRelatedWork W2127549094 @default.
• W2028294443 hasRelatedWork W2138608795 @default.
• W2028294443 hasRelatedWork W2392371029 @default.
• W2028294443 hasRelatedWork W2748952813 @default.
• W2028294443 hasVolume "27" @default.
• W2028294443 isParatext "false" @default.
• W2028294443 isRetracted "false" @default.
• W2028294443 magId "2028294443" @default.

• next