FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028346449> ?p ?o ?g. }

• W2028346449 endingPage "21" @default.
• W2028346449 startingPage "14" @default.
• W2028346449 abstract "We present a population balance model for enzyme deactivation and aggregation kinetics with a limited number of physically relevant parameters and use this model to analyse the experimental data for thermal inactivation of jack bean urease. The time dependence of the relative enzymatic activity was found to follow the second order kinetics, which was consistent with pre-equilibrated folding/unfolding of the native enzyme, followed by irreversible cluster–cluster aggregation of the non-native enzyme resulting in gradual and permanent loss of enzymatic activity. Monomer–cluster aggregation scenario was considered but was not consistent with the observed kinetic order of monomer disappearance at longer times. We analysed time evolution of the average hydrodynamic radius obtained from dynamic light scattering measurements and by fitting these data with our model, we were able to estimate the value of the unfolding equilibrium constant with a reasonable accuracy (Kc≈0.05 at 80 °C). We were also able to make order of magnitude estimates of the maximum number of enzyme molecules in the aggregated clusters (hundreds) as well as the aggregation rate constant of the non-native enzyme." @default.
• W2028346449 created "2016-06-24" @default.
• W2028346449 creator A5018716199 @default.
• W2028346449 creator A5021930675 @default.
• W2028346449 creator A5056795122 @default.
• W2028346449 creator A5081721251 @default.
• W2028346449 date "2012-03-01" @default.
• W2028346449 modified "2023-09-23" @default.
• W2028346449 title "Thermally induced inactivation and aggregation of urease: Experiments and population balance modelling" @default.
• W2028346449 cites W1511494479 @default.
• W2028346449 cites W1965238013 @default.
• W2028346449 cites W1970326310 @default.
• W2028346449 cites W1971759879 @default.
• W2028346449 cites W1973425278 @default.
• W2028346449 cites W1974598593 @default.
• W2028346449 cites W1993776218 @default.
• W2028346449 cites W1998752513 @default.
• W2028346449 cites W2006801807 @default.
• W2028346449 cites W2008992054 @default.
• W2028346449 cites W2010216657 @default.
• W2028346449 cites W2033042388 @default.
• W2028346449 cites W2034492780 @default.
• W2028346449 cites W2035536309 @default.
• W2028346449 cites W2035762247 @default.
• W2028346449 cites W2036644504 @default.
• W2028346449 cites W2046400129 @default.
• W2028346449 cites W205739566 @default.
• W2028346449 cites W2058469726 @default.
• W2028346449 cites W2061329137 @default.
• W2028346449 cites W2069665034 @default.
• W2028346449 cites W2079356186 @default.
• W2028346449 cites W2080766452 @default.
• W2028346449 cites W2081255144 @default.
• W2028346449 cites W2094870019 @default.
• W2028346449 cites W2096522200 @default.
• W2028346449 cites W2133323931 @default.
• W2028346449 cites W2151836578 @default.
• W2028346449 cites W2160406491 @default.
• W2028346449 cites W2162404049 @default.
• W2028346449 doi "https://doi.org/10.1016/j.ces.2011.07.050" @default.
• W2028346449 hasPublicationYear "2012" @default.
• W2028346449 type Work @default.
• W2028346449 sameAs 2028346449 @default.
• W2028346449 citedByCount "11" @default.
• W2028346449 countsByYear W20283464492014 @default.
• W2028346449 countsByYear W20283464492015 @default.
• W2028346449 countsByYear W20283464492017 @default.
• W2028346449 countsByYear W20283464492018 @default.
• W2028346449 countsByYear W20283464492019 @default.
• W2028346449 countsByYear W20283464492020 @default.
• W2028346449 crossrefType "journal-article" @default.
• W2028346449 hasAuthorship W2028346449A5018716199 @default.
• W2028346449 hasAuthorship W2028346449A5021930675 @default.
• W2028346449 hasAuthorship W2028346449A5056795122 @default.
• W2028346449 hasAuthorship W2028346449A5081721251 @default.
• W2028346449 hasConcept C119599485 @default.
• W2028346449 hasConcept C121332964 @default.
• W2028346449 hasConcept C127413603 @default.
• W2028346449 hasConcept C135694725 @default.
• W2028346449 hasConcept C136238340 @default.
• W2028346449 hasConcept C144024400 @default.
• W2028346449 hasConcept C148898269 @default.
• W2028346449 hasConcept C149923435 @default.
• W2028346449 hasConcept C159467904 @default.
• W2028346449 hasConcept C164866538 @default.
• W2028346449 hasConcept C166940927 @default.
• W2028346449 hasConcept C178635117 @default.
• W2028346449 hasConcept C178790620 @default.
• W2028346449 hasConcept C181199279 @default.
• W2028346449 hasConcept C185592680 @default.
• W2028346449 hasConcept C199360897 @default.
• W2028346449 hasConcept C2776545253 @default.
• W2028346449 hasConcept C2908647359 @default.
• W2028346449 hasConcept C38652104 @default.
• W2028346449 hasConcept C41008148 @default.
• W2028346449 hasConcept C41183919 @default.
• W2028346449 hasConcept C521977710 @default.
• W2028346449 hasConcept C55493867 @default.
• W2028346449 hasConcept C56856141 @default.
• W2028346449 hasConcept C62520636 @default.
• W2028346449 hasConcept C93391505 @default.
• W2028346449 hasConcept C97355855 @default.
• W2028346449 hasConceptScore W2028346449C119599485 @default.
• W2028346449 hasConceptScore W2028346449C121332964 @default.
• W2028346449 hasConceptScore W2028346449C127413603 @default.
• W2028346449 hasConceptScore W2028346449C135694725 @default.
• W2028346449 hasConceptScore W2028346449C136238340 @default.
• W2028346449 hasConceptScore W2028346449C144024400 @default.
• W2028346449 hasConceptScore W2028346449C148898269 @default.
• W2028346449 hasConceptScore W2028346449C149923435 @default.
• W2028346449 hasConceptScore W2028346449C159467904 @default.
• W2028346449 hasConceptScore W2028346449C164866538 @default.
• W2028346449 hasConceptScore W2028346449C166940927 @default.
• W2028346449 hasConceptScore W2028346449C178635117 @default.
• W2028346449 hasConceptScore W2028346449C178790620 @default.
• W2028346449 hasConceptScore W2028346449C181199279 @default.
• W2028346449 hasConceptScore W2028346449C185592680 @default.
• W2028346449 hasConceptScore W2028346449C199360897 @default.

• next