FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028351296> ?p ?o ?g. }

• W2028351296 endingPage "35" @default.
• W2028351296 startingPage "15" @default.
• W2028351296 abstract "Interrogating immune correlates of infection risk for efficacious and non-efficacious HIV-1 vaccine clinical trials have provided hypotheses regarding the mechanisms of induction of protective immunity to HIV-1. To date, there have been six HIV-1 vaccine efficacy trials (VAX003, Vaxgen, Inc., San Francisco, CA, USA), VAX004 (Vaxgen, Inc.), HIV-1 Vaccine Trials Network (HVTN) 502 (Step), HVTN 503 (Phambili), RV144 (sponsored by the U.S. Military HIV Research Program, MHRP) and HVTN 505). Cellular, humoral, host genetic and virus sieve analyses of these human clinical trials each can provide information that may point to potentially protective mechanisms for vaccine-induced immunity. Critical to staying on the path toward development of an efficacious vaccine is utilizing information from previous human and non-human primate studies in concert with new discoveries of basic HIV-1 host-virus interactions. One way that past discoveries from correlate analyses can lead to novel inventions or new pathways toward vaccine efficacy is to examine the intersections where different components of the correlate analyses overlap (e.g., virus sieve analysis combined with humoral correlates) that can point to mechanistic hypotheses. Additionally, differences in durability among vaccine-induced T- and B-cell responses indicate that time post-vaccination is an important variable. Thus, understanding the nature of protective responses, the degree to which such responses have, or have not, as yet, been induced by previous vaccine trials and the design of strategies to induce durable T- and B-cell responses are critical to the development of a protective HIV-1 vaccine." @default.
• W2028351296 created "2016-06-24" @default.
• W2028351296 creator A5034536696 @default.
• W2028351296 creator A5051827275 @default.
• W2028351296 date "2013-12-27" @default.
• W2028351296 modified "2023-09-27" @default.
• W2028351296 title "Advancing Toward HIV-1 Vaccine Efficacy through the Intersections of Immune Correlates" @default.
• W2028351296 cites W1655510925 @default.
• W2028351296 cites W1887985700 @default.
• W2028351296 cites W1966607693 @default.
• W2028351296 cites W1970749005 @default.
• W2028351296 cites W1976852477 @default.
• W2028351296 cites W1984591972 @default.
• W2028351296 cites W1985145726 @default.
• W2028351296 cites W2002116074 @default.
• W2028351296 cites W2002963026 @default.
• W2028351296 cites W2007837266 @default.
• W2028351296 cites W2016097275 @default.
• W2028351296 cites W2019405644 @default.
• W2028351296 cites W2026161149 @default.
• W2028351296 cites W2026562276 @default.
• W2028351296 cites W2028101850 @default.
• W2028351296 cites W2034100391 @default.
• W2028351296 cites W2043944957 @default.
• W2028351296 cites W2046471199 @default.
• W2028351296 cites W2051163112 @default.
• W2028351296 cites W2060119188 @default.
• W2028351296 cites W2061949672 @default.
• W2028351296 cites W2063396456 @default.
• W2028351296 cites W2065353103 @default.
• W2028351296 cites W2075345074 @default.
• W2028351296 cites W2076195337 @default.
• W2028351296 cites W2076826583 @default.
• W2028351296 cites W2079792142 @default.
• W2028351296 cites W2080084242 @default.
• W2028351296 cites W2082238185 @default.
• W2028351296 cites W2083930921 @default.
• W2028351296 cites W2085919513 @default.
• W2028351296 cites W2086382571 @default.
• W2028351296 cites W2102296058 @default.
• W2028351296 cites W2104823480 @default.
• W2028351296 cites W2104851804 @default.
• W2028351296 cites W2108823547 @default.
• W2028351296 cites W2108868448 @default.
• W2028351296 cites W2113226921 @default.
• W2028351296 cites W2114114918 @default.
• W2028351296 cites W2116834921 @default.
• W2028351296 cites W2122345805 @default.
• W2028351296 cites W2131674674 @default.
• W2028351296 cites W2131896393 @default.
• W2028351296 cites W2136286344 @default.
• W2028351296 cites W2138957964 @default.
• W2028351296 cites W2139575047 @default.
• W2028351296 cites W2143421242 @default.
• W2028351296 cites W2148814575 @default.
• W2028351296 cites W2149551637 @default.
• W2028351296 cites W2152048324 @default.
• W2028351296 cites W2152254666 @default.
• W2028351296 cites W2152534166 @default.
• W2028351296 cites W2152640863 @default.
• W2028351296 cites W2153670011 @default.
• W2028351296 cites W2156885603 @default.
• W2028351296 cites W2157371332 @default.
• W2028351296 cites W2157903295 @default.
• W2028351296 cites W2160925670 @default.
• W2028351296 cites W2162822797 @default.
• W2028351296 cites W2162891851 @default.
• W2028351296 cites W2164147266 @default.
• W2028351296 cites W2240372320 @default.
• W2028351296 cites W2319049392 @default.
• W2028351296 doi "https://doi.org/10.3390/vaccines2010015" @default.
• W2028351296 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4053939" @default.
• W2028351296 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24932411" @default.
• W2028351296 hasPublicationYear "2013" @default.
• W2028351296 type Work @default.
• W2028351296 sameAs 2028351296 @default.
• W2028351296 citedByCount "40" @default.
• W2028351296 countsByYear W20283512962014 @default.
• W2028351296 countsByYear W20283512962015 @default.
• W2028351296 countsByYear W20283512962016 @default.
• W2028351296 countsByYear W20283512962017 @default.
• W2028351296 countsByYear W20283512962018 @default.
• W2028351296 countsByYear W20283512962019 @default.
• W2028351296 countsByYear W20283512962020 @default.
• W2028351296 countsByYear W20283512962021 @default.
• W2028351296 countsByYear W20283512962022 @default.
• W2028351296 countsByYear W20283512962023 @default.
• W2028351296 crossrefType "journal-article" @default.
• W2028351296 hasAuthorship W2028351296A5034536696 @default.
• W2028351296 hasAuthorship W2028351296A5051827275 @default.
• W2028351296 hasBestOaLocation W20283512961 @default.
• W2028351296 hasConcept C126322002 @default.
• W2028351296 hasConcept C159047783 @default.
• W2028351296 hasConcept C203014093 @default.
• W2028351296 hasConcept C22070199 @default.
• W2028351296 hasConcept C2778190748 @default.
• W2028351296 hasConcept C2779341262 @default.
• W2028351296 hasConcept C2780195530 @default.

• next