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• W2028367026 endingPage "365" @default.
• W2028367026 startingPage "356" @default.
• W2028367026 abstract "We assessed the effects of single-nucleotide polymorphisms (SNPs) within the porcine fatty acid synthase (FASN) gene regarding meat quality and fatty acid composition in two pig populations: Korean native pigs (KNP) were crossed with Yorkshire (YS) <TEX>$F_2$</TEX>, and KNP were crossed with Landrace (LR) <TEX>$F_2$</TEX>. Direct DNA sequencing using eight KNP and eight YS pigs revealed two SNPs: c.265C>T (silent) in exon 4 and c.6545A>C (Asn<TEX>${rightarrow}$</TEX>His) in exon 39. The frequency of the two SNPs was analyzed using the polymerase chain reaction-restriction fragment length polymorphism method in seven pig breeds and their association with meat quality traits and fatty acid composition was studied. In the <TEX>$KNP{times}YSF_2$</TEX> population, both SNPs were significantly associated with the level of monounsaturated fatty acids, including palmitoleic (C16:1) and oleic acid (C18:1) (p<0.005). c.6545A>C was associated with intramuscular fat content in both populations. Our results indicate that variations in c.265C>T and c.6545A>C of the pig FASN can be used to select animals with better fatty acid composition and meat quality. Moreover, KNP was a useful breed for identifying genetic factors affecting meat quality and fatty acid composition and for producing high quality pork." @default.
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• W2028367026 date "2011-06-30" @default.
• W2028367026 modified "2023-10-14" @default.
• W2028367026 title "Porcine Fatty Acid Synthase Gene Polymorphisms Are Associated with Meat Quality and Fatty Acid Composition" @default.
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• W2028367026 doi "https://doi.org/10.5851/kosfa.2011.31.3.356" @default.
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