Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028388637> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2028388637 endingPage "70" @default.
- W2028388637 startingPage "S68" @default.
- W2028388637 abstract "Summary: Cleavage sites of porcine big endothelin-1 (big ET-1, 1 −39) by cathepsin D were examined and compared with those by other aspartic proteinases including pepsin. Cathepsin D cleaved not only the Trp21-Val22 bond, but also the Asp18-Ile19 bond of big ET-l[l-39]. The mature ET-1 [ 1 −21 ], generated by the cleavage between Trp21 and Val22, was subsequently degraded by removal of the C-terminal tripeptide (Ile21-Ile20-Trp21). On the other hand, pepsin cleaved the Trp21-Val22 bond of big ET-1 [ I-39] to produce ET-1 [ 1–21 ]. but did not degrade the generated ET-1 [ 1 −21 ]. These results indicate that aspartic proteinases such as cathepsin D and pepsin are capable of converting big ET-1 [1–39] to ET-1 [ 1 −21 ], whereas the former proteinase is by no means specific for the Trp21-Val22 bond of big ET-l[l-39]." @default.
- W2028388637 created "2016-06-24" @default.
- W2028388637 creator A5003414522 @default.
- W2028388637 creator A5015371472 @default.
- W2028388637 creator A5016752876 @default.
- W2028388637 creator A5019991784 @default.
- W2028388637 creator A5080438609 @default.
- W2028388637 creator A5087094917 @default.
- W2028388637 date "1991-01-01" @default.
- W2028388637 modified "2023-09-23" @default.
- W2028388637 title "Mode of Cleavage of Porcine Big Endothelin-1 by Aspartic Proteinases" @default.
- W2028388637 doi "https://doi.org/10.1097/00005344-199100177-00019" @default.
- W2028388637 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1725436" @default.
- W2028388637 hasPublicationYear "1991" @default.
- W2028388637 type Work @default.
- W2028388637 sameAs 2028388637 @default.
- W2028388637 citedByCount "1" @default.
- W2028388637 crossrefType "journal-article" @default.
- W2028388637 hasAuthorship W2028388637A5003414522 @default.
- W2028388637 hasAuthorship W2028388637A5015371472 @default.
- W2028388637 hasAuthorship W2028388637A5016752876 @default.
- W2028388637 hasAuthorship W2028388637A5019991784 @default.
- W2028388637 hasAuthorship W2028388637A5080438609 @default.
- W2028388637 hasAuthorship W2028388637A5087094917 @default.
- W2028388637 hasBestOaLocation W20283886371 @default.
- W2028388637 hasConcept C151730666 @default.
- W2028388637 hasConcept C153911025 @default.
- W2028388637 hasConcept C16311235 @default.
- W2028388637 hasConcept C167392928 @default.
- W2028388637 hasConcept C167844969 @default.
- W2028388637 hasConcept C173633252 @default.
- W2028388637 hasConcept C175156509 @default.
- W2028388637 hasConcept C181199279 @default.
- W2028388637 hasConcept C185592680 @default.
- W2028388637 hasConcept C2779281246 @default.
- W2028388637 hasConcept C31684184 @default.
- W2028388637 hasConcept C43369102 @default.
- W2028388637 hasConcept C55493867 @default.
- W2028388637 hasConcept C71240020 @default.
- W2028388637 hasConcept C86803240 @default.
- W2028388637 hasConceptScore W2028388637C151730666 @default.
- W2028388637 hasConceptScore W2028388637C153911025 @default.
- W2028388637 hasConceptScore W2028388637C16311235 @default.
- W2028388637 hasConceptScore W2028388637C167392928 @default.
- W2028388637 hasConceptScore W2028388637C167844969 @default.
- W2028388637 hasConceptScore W2028388637C173633252 @default.
- W2028388637 hasConceptScore W2028388637C175156509 @default.
- W2028388637 hasConceptScore W2028388637C181199279 @default.
- W2028388637 hasConceptScore W2028388637C185592680 @default.
- W2028388637 hasConceptScore W2028388637C2779281246 @default.
- W2028388637 hasConceptScore W2028388637C31684184 @default.
- W2028388637 hasConceptScore W2028388637C43369102 @default.
- W2028388637 hasConceptScore W2028388637C55493867 @default.
- W2028388637 hasConceptScore W2028388637C71240020 @default.
- W2028388637 hasConceptScore W2028388637C86803240 @default.
- W2028388637 hasLocation W20283886371 @default.
- W2028388637 hasLocation W20283886372 @default.
- W2028388637 hasLocation W20283886373 @default.
- W2028388637 hasOpenAccess W2028388637 @default.
- W2028388637 hasPrimaryLocation W20283886371 @default.
- W2028388637 hasRelatedWork W168461730 @default.
- W2028388637 hasRelatedWork W1760686898 @default.
- W2028388637 hasRelatedWork W1856425029 @default.
- W2028388637 hasRelatedWork W2004754196 @default.
- W2028388637 hasRelatedWork W2007946324 @default.
- W2028388637 hasRelatedWork W2028388637 @default.
- W2028388637 hasRelatedWork W2038276885 @default.
- W2028388637 hasRelatedWork W2064589367 @default.
- W2028388637 hasRelatedWork W2072055568 @default.
- W2028388637 hasRelatedWork W2228175964 @default.
- W2028388637 hasVolume "17" @default.
- W2028388637 isParatext "false" @default.
- W2028388637 isRetracted "false" @default.
- W2028388637 magId "2028388637" @default.
- W2028388637 workType "article" @default.