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- W2028405909 abstract "Considerable data have been gathered on intra-arterial drug infusion via infusion pumps. The pharmacokinetic theory underlying the principles of intra-arterial drug administration are well described. Although some examples can be found of successful administration of drugs by the intra-arterial route, other drugs have yielded disappointing results. In this paper it is argued that the apparent failure of the intra-arterial route, both clinically and experimentally, is due to a lack of relevant consideration of pharmacokinetics. Examples are described in which the probability of successful intra-arterial drug administration is enhanced substantially by considerations of the relevant pharmacokinetic factors." @default.
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- W2028405909 date "1991-01-01" @default.
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- W2028405909 title "Pharmacokinetic considerations in local drug delivery" @default.
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- W2028405909 doi "https://doi.org/10.1016/0169-409x(91)90029-c" @default.
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