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- W2028419342 abstract "Inclusion complexation between veronicafolin, 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone, and β-cyclodextrin (β-CD) was investigated by using 1H NMR, IR, X-ray diffraction, thermo gravimetric analysis (TGA), and elemental analysis in the solid state. The elemental analysis showed that the complex (1:1) of flavonol-β-CD·20H2O with C 39.58% and H 5.75% has been formed. The phase solubility profile of the favonol by UV-Vis in solution in the presence of hydroxypfropyl-β-cyclodextrin (HP-β-CD) was classified as AL-type, indicating the formation of 1:1 inclusion complex. And the calibration equation y=24148x+0.0075 (r=0.9999) and phase-solubility diagram y=0.4738x-2.0×10-7 (r=0.9490) were obtained. Stability constant Ks was calculated from the phase solubility diagram (Ks=4.5×106). Solubility of the veronicafolin was enhanced in the presence of HP-β-CD." @default.
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- W2028419342 date "2005-06-01" @default.
- W2028419342 modified "2023-09-27" @default.
- W2028419342 title "Physicochemical Characterization of Veronicafolin-β-cyclodextrin and Solubility Enhancement of Veronicafolin-HP-β-cyclodextrin Inclusion Compound" @default.
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- W2028419342 doi "https://doi.org/10.1002/cjoc.200590775" @default.
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