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- W2028448406 abstract "Objective: To provide a comprehensive review of the issue related to the administration of sedative, analgesic, and neuromuscular blocking agents (NMBA) to patients who are receiving ventilatory support for acute respiratory distress syndrome (ARDS) with high-frequency oscillatory ventilation. Results: Sedative, analgesic, and NMBA are used with great frequency in patients with severe ARDS who are undergoing high-frequency oscillatory ventilation. In particular, the use of NMBA has been higher than for other ARDS populations. Important considerations for effective treatment include careful patient evaluation, patient-based medication selection, identification of treatment goals with periodic re-assessment, titration of medications to objective parameters such as sedation scales and peripheral nerve stimulation, use of intermittent therapy when feasible, implementation of drug interruption strategies, and discontinuation of medications at the earliest possible time. It is important to recognize that patients evolve from severe ARDS through phases of recovery to the resolution of respiratory failure and that ventilatory management, as well as sedative and related medication requirements, will vary markedly over the course of this process. Conclusions: A multidisciplinary, structured approach that is based on the considerations described should help achieve optimal results in this challenging patient population." @default.
- W2028448406 created "2016-06-24" @default.
- W2028448406 creator A5032689804 @default.
- W2028448406 date "2005-03-01" @default.
- W2028448406 modified "2023-09-25" @default.
- W2028448406 title "Sedation, analgesia, and neuromuscular blockade for high-frequency oscillatory ventilation" @default.
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- W2028448406 doi "https://doi.org/10.1097/01.ccm.0000156794.96880.df" @default.
- W2028448406 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15753730" @default.
- W2028448406 hasPublicationYear "2005" @default.
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