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- W2028456472 abstract "therapy, radioisotopes are placed in a cavity, such as the uterine cavity or vagina. Cervical cancer can be treated with this technique. In interstitial brachytherapy, small radioisotope sources are directly inserted into the tumor. Tongue cancer and prostate cancer can be treated with this technique. Bile duct cancer and bronchial cancer can be treated with intraluminal brachytherapy. In LDR brachytherapy, small sources of Cs-137 and Ir192 are temporarily implanted, and those of Au-198, I-125, and Pd-103 are permanently implanted. There is another problem with LDR brachytherapy, as well as the problem of radiation exposure to medical staff. The supply of new sources of Cs-137, Sr-90, and other radioisotopes has now stopped. The working life of the small sources is only 10 years, and after 10 years, these sources must be checked for leakage at an authorized institute. In the near future, we will be able to use only Ir-192 for temporary implantation. As already mentioned, brachytherapy has the advantage of providing localized radiation to the tumor with minimal radiation to the normal surrounding tissues. However, LDR brachytherapy has the disadvantages of radiation exposure to medical staff and the need for isolation of the patient in a highly shielded room. In HDR, patients are treated with RALS. Using RALS, there is no radiation exposure to the medical staff, and isolation of the patient is not needed. In Japan, HDR brachytherapy is mainly used for cervical cancer. LDR brachytherapy can be employed for only limited numbers of patients in Japanese hospitals; fi rstly, because highly shielded rooms are needed, and secondly because the regulation of radioisotopes is very strict in Japan. It is very diffi cult to start LDR brachytherapy, except that in which I-125 seeds are used; because of their low energy, it is easy to protect staff from I-125 radiation. Treatment of prostate cancer with I-125 seeds is employed in more than 100 hospitals in Japan. In this issue of the International Journal of Clinical Oncology, there are four review articles on brachytherapy: for head and neck cancer, for breast cancer, for cervical cancer, and for prostate cancer. These present the current status of and perspectives on brachytherapy. Received: November 18, 2008" @default.
- W2028456472 created "2016-06-24" @default.
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- W2028456472 date "2009-02-01" @default.
- W2028456472 modified "2023-09-27" @default.
- W2028456472 title "Current status and perspectives of brachytherapy" @default.
- W2028456472 doi "https://doi.org/10.1007/s10147-008-0862-3" @default.
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