FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028461446> ?p ?o ?g. }

• W2028461446 endingPage "739" @default.
• W2028461446 startingPage "735" @default.
• W2028461446 abstract "OBJECTIVE: To determine the risk factors for aminoglycoside toxicity in the elderly. DESIGN: Prospective observational study. SETTING: Acute care teaching hospital serving predominantly veterans. PARTICIPANTS: Consecutive patients aged 70 years and over receiving aminoglycosides. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Thirteen (15%) of 88 patients developed aminoglycoside-related nephrotoxicity and 3 (3.4%) developed otovestibular toxicity. Multivariate analysis showed that increasing duration of aminoglycoside therapy was the only factor significantly associated with development of toxicity. Elevated baseline serum creatinine level (p=.02) and use of allopurinol (p=.03) were risk factors specifically for nephrotoxicity. Only 2 (3.9%) of 51 patients receiving aminoglycosides 7 or fewer days developed nephrotoxicity, as compared with 11 (30%) of 37 receiving the drugs for 8 to 14 days and 4 (50%) of 8 treated for more than 14 days. CONCLUSIONS: Although toxicity is common in elderly patients treated with aminoglycosides, limiting the duration of aminoglycoside therapy to less than a week can substantially reduce risk of toxicity." @default.
• W2028461446 created "2016-06-24" @default.
• W2028461446 creator A5015076483 @default.
• W2028461446 creator A5020920868 @default.
• W2028461446 creator A5029036100 @default.
• W2028461446 date "1998-11-01" @default.
• W2028461446 modified "2023-09-24" @default.
• W2028461446 title "Risk factors for toxicity in elderly patients given aminoglycosides once daily" @default.
• W2028461446 cites W1550111394 @default.
• W2028461446 cites W1991811123 @default.
• W2028461446 cites W1993014466 @default.
• W2028461446 cites W1997423693 @default.
• W2028461446 cites W2000307487 @default.
• W2028461446 cites W2008294830 @default.
• W2028461446 cites W2014709078 @default.
• W2028461446 cites W2025801951 @default.
• W2028461446 cites W2042241561 @default.
• W2028461446 cites W2048478051 @default.
• W2028461446 cites W2088188414 @default.
• W2028461446 cites W2100907980 @default.
• W2028461446 cites W2122316430 @default.
• W2028461446 cites W2126520713 @default.
• W2028461446 cites W2144540367 @default.
• W2028461446 cites W2167293877 @default.
• W2028461446 cites W2167768564 @default.
• W2028461446 cites W2404125892 @default.
• W2028461446 cites W2411135423 @default.
• W2028461446 cites W2411564459 @default.
• W2028461446 cites W2416244716 @default.
• W2028461446 cites W2418348943 @default.
• W2028461446 cites W2463894061 @default.
• W2028461446 cites W3134263331 @default.
• W2028461446 cites W4240011334 @default.
• W2028461446 doi "https://doi.org/10.1046/j.1525-1497.1998.00224.x" @default.
• W2028461446 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1497032" @default.
• W2028461446 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9824518" @default.
• W2028461446 hasPublicationYear "1998" @default.
• W2028461446 type Work @default.
• W2028461446 sameAs 2028461446 @default.
• W2028461446 citedByCount "98" @default.
• W2028461446 countsByYear W20284614462012 @default.
• W2028461446 countsByYear W20284614462013 @default.
• W2028461446 countsByYear W20284614462014 @default.
• W2028461446 countsByYear W20284614462015 @default.
• W2028461446 countsByYear W20284614462016 @default.
• W2028461446 countsByYear W20284614462017 @default.
• W2028461446 countsByYear W20284614462018 @default.
• W2028461446 countsByYear W20284614462019 @default.
• W2028461446 countsByYear W20284614462020 @default.
• W2028461446 countsByYear W20284614462021 @default.
• W2028461446 countsByYear W20284614462022 @default.
• W2028461446 countsByYear W20284614462023 @default.
• W2028461446 crossrefType "journal-article" @default.
• W2028461446 hasAuthorship W2028461446A5015076483 @default.
• W2028461446 hasAuthorship W2028461446A5020920868 @default.
• W2028461446 hasAuthorship W2028461446A5029036100 @default.
• W2028461446 hasBestOaLocation W20284614462 @default.
• W2028461446 hasConcept C126189478 @default.
• W2028461446 hasConcept C126322002 @default.
• W2028461446 hasConcept C177713679 @default.
• W2028461446 hasConcept C188816634 @default.
• W2028461446 hasConcept C2777787772 @default.
• W2028461446 hasConcept C2780306776 @default.
• W2028461446 hasConcept C29730261 @default.
• W2028461446 hasConcept C501593827 @default.
• W2028461446 hasConcept C50440223 @default.
• W2028461446 hasConcept C71924100 @default.
• W2028461446 hasConcept C86803240 @default.
• W2028461446 hasConcept C89423630 @default.
• W2028461446 hasConceptScore W2028461446C126189478 @default.
• W2028461446 hasConceptScore W2028461446C126322002 @default.
• W2028461446 hasConceptScore W2028461446C177713679 @default.
• W2028461446 hasConceptScore W2028461446C188816634 @default.
• W2028461446 hasConceptScore W2028461446C2777787772 @default.
• W2028461446 hasConceptScore W2028461446C2780306776 @default.
• W2028461446 hasConceptScore W2028461446C29730261 @default.
• W2028461446 hasConceptScore W2028461446C501593827 @default.
• W2028461446 hasConceptScore W2028461446C50440223 @default.
• W2028461446 hasConceptScore W2028461446C71924100 @default.
• W2028461446 hasConceptScore W2028461446C86803240 @default.
• W2028461446 hasConceptScore W2028461446C89423630 @default.
• W2028461446 hasIssue "11" @default.
• W2028461446 hasLocation W20284614461 @default.
• W2028461446 hasLocation W20284614462 @default.
• W2028461446 hasLocation W20284614463 @default.
• W2028461446 hasLocation W20284614464 @default.
• W2028461446 hasOpenAccess W2028461446 @default.
• W2028461446 hasPrimaryLocation W20284614461 @default.
• W2028461446 hasRelatedWork W1480522522 @default.
• W2028461446 hasRelatedWork W1968078392 @default.
• W2028461446 hasRelatedWork W2080661383 @default.
• W2028461446 hasRelatedWork W2085081793 @default.
• W2028461446 hasRelatedWork W2106188053 @default.
• W2028461446 hasRelatedWork W2182583249 @default.
• W2028461446 hasRelatedWork W2394819023 @default.
• W2028461446 hasRelatedWork W2467273834 @default.
• W2028461446 hasRelatedWork W2522770223 @default.
• W2028461446 hasRelatedWork W2902628420 @default.

• next