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• W2028483600 abstract "A new three-dimensional (3D) scaffold containing a functional drug delivery system (DDS) consisting of electrospun micro/nanofibers is proposed. In the DDS scaffold, a core-shell laminated, structured, electrospun mat of hydrophobic polycaprolactone (PCL) and hydrophilic poly(ethylene oxide) (PEO)/rhodamine-B fibers was embedded in the normal 3D PCL scaffold, which was fabricated by a melt-plotting system. Rhodamine release from the scaffold was controlled physically by the thickness change of the PCL layer, and initial burst in drug release was eliminated by an appropriate thickness of the PCL layer. This simple technique may be useful in fabricating DDS-functional scaffolds for the clinical areas not only of bone and skin regeneration, but also of other tissue regeneration areas, regardless of the degradation rate of the structural scaffold." @default.
• W2028483600 created "2016-06-24" @default.
• W2028483600 creator A5029599239 @default.
• W2028483600 creator A5088071932 @default.
• W2028483600 date "2011-02-01" @default.
• W2028483600 modified "2023-09-28" @default.
• W2028483600 title "A Three-Dimensional Polycaprolactone Scaffold Combined with a Drug Delivery System Consisting of Electrospun Nanofibers" @default.
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• W2028483600 doi "https://doi.org/10.1002/jps.22310" @default.
• W2028483600 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20740676" @default.
• W2028483600 hasPublicationYear "2011" @default.
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