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• W2028496489 abstract "Excessive levels of glucocorticoids have been implicated in the etiology of affective disorders in humans, and in a range of behavioral deficits in animals. In the present study, we used an established regimen of corticosterone administration (40 mg/kg, for 21 days) to determine its effects upon responding for rewarding brain stimulation in rats. After chronic treatment, subjects exhibited an unexpected but significantly increased sensitivity to the rewarding effects of brain stimulation. These results suggest that chronic, high levels of corticosterone are unlikely to cause anhedonia in rodents." @default.
• W2028496489 created "2016-06-24" @default.
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• W2028496489 date "2000-09-01" @default.
• W2028496489 modified "2023-09-27" @default.
• W2028496489 title "Chronic corticosterone enhances the rewarding effect of hypothalamic self-stimulation in rats" @default.
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• W2028496489 doi "https://doi.org/10.1016/s0006-8993(00)02652-4" @default.
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