Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028497037> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2028497037 endingPage "256" @default.
- W2028497037 startingPage "252" @default.
- W2028497037 abstract "Specific antibody responses to influenza virus were obtained in vitro from human blood mononuclear cells (PBMC). Antibody production in these cultures was profoundly suppressed by the addition of allogeneic T cells with the surface phenotype Leu2a+ (CD8+), Leu8−. Suppression by allogeneic T suppressor (Ts) cells required interactions only between T-depleted B (E−) cells and allogeneic Leu2a+. No evidence was obtained for T-T cell interactions, or for Ts inducer cells similar to those described for nonspecific antibody responses to pokeweed mitogen. Moreover, allogeneic E+, or allogeneic Leu2a+ cells were able to suppress specific antibody responses by E− cells when help was provided by T cell-replacing factor showing that the target of suppression was the responding E− cells, and not T helper cells. In contrast to allogeneic T cells, allogeneic E− cells did not suppress antibody production when added to cultures of unfractionated PBMC (E− + E+). That is, Ts cells activated to allogeneic E− were unable to suppress antibody production by the syngeneic E− cells present in the same culture tube. This result shows that alloactivated Ts cells were specific for the allogeneic E− target cells, and that suppression was not mediated by nonspecific allogeneic effects. Allogeneic Ts cells therefore differ from Ts cells in pokeweed mitogen responses by their specificity, and by their activation in the absence of Ts inducer cells." @default.
- W2028497037 created "2016-06-24" @default.
- W2028497037 creator A5025217856 @default.
- W2028497037 creator A5049495804 @default.
- W2028497037 creator A5078521032 @default.
- W2028497037 date "1986-01-01" @default.
- W2028497037 modified "2023-10-14" @default.
- W2028497037 title "Antigen-specific suppression of human antibody responses by allogeneic T cells II. Cell interactions involved in the generation of suppression" @default.
- W2028497037 cites W1973103992 @default.
- W2028497037 cites W1979540938 @default.
- W2028497037 cites W1984191272 @default.
- W2028497037 cites W1984555358 @default.
- W2028497037 cites W1984836875 @default.
- W2028497037 cites W1986293304 @default.
- W2028497037 cites W2001349905 @default.
- W2028497037 cites W2006330221 @default.
- W2028497037 cites W2026692661 @default.
- W2028497037 cites W2032905651 @default.
- W2028497037 cites W2038735650 @default.
- W2028497037 cites W2042758073 @default.
- W2028497037 cites W2045798674 @default.
- W2028497037 cites W2047218350 @default.
- W2028497037 cites W2050745720 @default.
- W2028497037 cites W2068803746 @default.
- W2028497037 cites W2074614649 @default.
- W2028497037 cites W2076288161 @default.
- W2028497037 cites W2076749285 @default.
- W2028497037 cites W2089248242 @default.
- W2028497037 cites W2113095984 @default.
- W2028497037 cites W2125180137 @default.
- W2028497037 cites W2128677901 @default.
- W2028497037 cites W2154230619 @default.
- W2028497037 cites W2170701952 @default.
- W2028497037 cites W2335575025 @default.
- W2028497037 doi "https://doi.org/10.1002/eji.1830160308" @default.
- W2028497037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2937641" @default.
- W2028497037 hasPublicationYear "1986" @default.
- W2028497037 type Work @default.
- W2028497037 sameAs 2028497037 @default.
- W2028497037 citedByCount "6" @default.
- W2028497037 crossrefType "journal-article" @default.
- W2028497037 hasAuthorship W2028497037A5025217856 @default.
- W2028497037 hasAuthorship W2028497037A5049495804 @default.
- W2028497037 hasAuthorship W2028497037A5078521032 @default.
- W2028497037 hasConcept C129374314 @default.
- W2028497037 hasConcept C137061746 @default.
- W2028497037 hasConcept C147483822 @default.
- W2028497037 hasConcept C153911025 @default.
- W2028497037 hasConcept C154317977 @default.
- W2028497037 hasConcept C159654299 @default.
- W2028497037 hasConcept C167672396 @default.
- W2028497037 hasConcept C202751555 @default.
- W2028497037 hasConcept C203014093 @default.
- W2028497037 hasConcept C2776090121 @default.
- W2028497037 hasConcept C2781005381 @default.
- W2028497037 hasConcept C39347974 @default.
- W2028497037 hasConcept C55493867 @default.
- W2028497037 hasConcept C86803240 @default.
- W2028497037 hasConcept C8891405 @default.
- W2028497037 hasConceptScore W2028497037C129374314 @default.
- W2028497037 hasConceptScore W2028497037C137061746 @default.
- W2028497037 hasConceptScore W2028497037C147483822 @default.
- W2028497037 hasConceptScore W2028497037C153911025 @default.
- W2028497037 hasConceptScore W2028497037C154317977 @default.
- W2028497037 hasConceptScore W2028497037C159654299 @default.
- W2028497037 hasConceptScore W2028497037C167672396 @default.
- W2028497037 hasConceptScore W2028497037C202751555 @default.
- W2028497037 hasConceptScore W2028497037C203014093 @default.
- W2028497037 hasConceptScore W2028497037C2776090121 @default.
- W2028497037 hasConceptScore W2028497037C2781005381 @default.
- W2028497037 hasConceptScore W2028497037C39347974 @default.
- W2028497037 hasConceptScore W2028497037C55493867 @default.
- W2028497037 hasConceptScore W2028497037C86803240 @default.
- W2028497037 hasConceptScore W2028497037C8891405 @default.
- W2028497037 hasIssue "3" @default.
- W2028497037 hasLocation W20284970371 @default.
- W2028497037 hasLocation W20284970372 @default.
- W2028497037 hasOpenAccess W2028497037 @default.
- W2028497037 hasPrimaryLocation W20284970371 @default.
- W2028497037 hasRelatedWork W2123317146 @default.
- W2028497037 hasRelatedWork W2139860153 @default.
- W2028497037 hasRelatedWork W2145562912 @default.
- W2028497037 hasRelatedWork W2148785609 @default.
- W2028497037 hasRelatedWork W2153742280 @default.
- W2028497037 hasRelatedWork W2270348304 @default.
- W2028497037 hasRelatedWork W2393477958 @default.
- W2028497037 hasRelatedWork W2403656428 @default.
- W2028497037 hasRelatedWork W2420090360 @default.
- W2028497037 hasRelatedWork W2437244344 @default.
- W2028497037 hasVolume "16" @default.
- W2028497037 isParatext "false" @default.
- W2028497037 isRetracted "false" @default.
- W2028497037 magId "2028497037" @default.
- W2028497037 workType "article" @default.