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- W2028499178 abstract "A new HPLC procedure for the determination of metronidazole, a nitroimidazole, in adult Artemia (live brine shrimp) has been developed and validated. Following a liquid extraction using methanol, samples were separated by isocratic reversed-phase HPLC on a Symmetry C18 column and quantified using UV detection at 324 nm. The mobile phase was a mixture of water and methanol, with a flow-rate of 1.0 ml/min. The procedure produced a linear curve over the concentration range 1-500 µg/gm with a lower limit of quantification of 0.25 µg/gm. Intra and inter-assay variability was less than 10%. The development of the assay allowed the determination of metronidazole in a live brine shrimp feeding study." @default.
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- W2028499178 date "2009-12-09" @default.
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- W2028499178 title "DETERMINATION OF METRONIDAZOLE IN ADULT <i>ARTEMIA</i> USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY" @default.
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- W2028499178 doi "https://doi.org/10.1080/10826070903430381" @default.
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