FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028505686> ?p ?o ?g. }

• W2028505686 endingPage "161" @default.
• W2028505686 startingPage "155" @default.
• W2028505686 abstract "Lactoferrin, a glycoprotein present in neutrophils and exocrine secretions, plays important roles in host defense. Administration of bovine lactoferrin has been reported to modulate various neutrophil functions. We found a mixed-breed male dog with novel familial neutrophil dysfunction. The disorder was caused by a decrease of β2-integrin expression encoding CD18 without mutation. Antibiotics therapy alone did not influence a series of neutrophil functions in the same dog. We examined the effects of oral administration of bovine lactoferrin on the neutrophil function and clinical symptoms in the same dog. Oral chronic administration of bovine lactoferrin increased neutrophilic β2-integrin gene expression comparable to normal dogs, followed by the upregulation of surface CD18 expression. Concurrently, the superoxide production, phagocytic activity and adherence that were β2-integrin-related neutrophil functions increased to normal canine levels. The chronic inflammation from bacterial upper respiratory infections and pneumonia was also alleviated in the dog. Our results indicate that oral treatment with bovine lactoferrin increases neutrophil β2-integrin transcript level, leading to the upregulation of neutrophil functions and improvement of clinical symptoms in the dog with familial neutrophil dysfunction." @default.
• W2028505686 created "2016-06-24" @default.
• W2028505686 creator A5001081902 @default.
• W2028505686 creator A5007968139 @default.
• W2028505686 creator A5053321780 @default.
• W2028505686 creator A5061663479 @default.
• W2028505686 creator A5067990152 @default.
• W2028505686 creator A5068497490 @default.
• W2028505686 creator A5072096798 @default.
• W2028505686 creator A5090343584 @default.
• W2028505686 date "2011-09-01" @default.
• W2028505686 modified "2023-09-28" @default.
• W2028505686 title "Oral administration of bovine lactoferrin upregulates neutrophil functions in a dog with familial β2-integrin-related neutrophil dysfunction" @default.
• W2028505686 cites W1484202205 @default.
• W2028505686 cites W1967485976 @default.
• W2028505686 cites W1971030180 @default.
• W2028505686 cites W1972995462 @default.
• W2028505686 cites W1981120093 @default.
• W2028505686 cites W1981193495 @default.
• W2028505686 cites W1987642463 @default.
• W2028505686 cites W2006726566 @default.
• W2028505686 cites W2016698655 @default.
• W2028505686 cites W2023313751 @default.
• W2028505686 cites W2050069950 @default.
• W2028505686 cites W2057627260 @default.
• W2028505686 cites W2063754132 @default.
• W2028505686 cites W2066768886 @default.
• W2028505686 cites W2067573063 @default.
• W2028505686 cites W2071378453 @default.
• W2028505686 cites W2086602979 @default.
• W2028505686 cites W2113423265 @default.
• W2028505686 cites W2122476363 @default.
• W2028505686 cites W2273926125 @default.
• W2028505686 cites W2469414933 @default.
• W2028505686 cites W72118013 @default.
• W2028505686 cites W73275066 @default.
• W2028505686 doi "https://doi.org/10.1016/j.vetimm.2011.05.027" @default.
• W2028505686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21676472" @default.
• W2028505686 hasPublicationYear "2011" @default.
• W2028505686 type Work @default.
• W2028505686 sameAs 2028505686 @default.
• W2028505686 citedByCount "7" @default.
• W2028505686 countsByYear W20285056862012 @default.
• W2028505686 countsByYear W20285056862013 @default.
• W2028505686 countsByYear W20285056862014 @default.
• W2028505686 countsByYear W20285056862018 @default.
• W2028505686 countsByYear W20285056862021 @default.
• W2028505686 crossrefType "journal-article" @default.
• W2028505686 hasAuthorship W2028505686A5001081902 @default.
• W2028505686 hasAuthorship W2028505686A5007968139 @default.
• W2028505686 hasAuthorship W2028505686A5053321780 @default.
• W2028505686 hasAuthorship W2028505686A5061663479 @default.
• W2028505686 hasAuthorship W2028505686A5067990152 @default.
• W2028505686 hasAuthorship W2028505686A5068497490 @default.
• W2028505686 hasAuthorship W2028505686A5072096798 @default.
• W2028505686 hasAuthorship W2028505686A5090343584 @default.
• W2028505686 hasBestOaLocation W20285056862 @default.
• W2028505686 hasConcept C104317684 @default.
• W2028505686 hasConcept C127561419 @default.
• W2028505686 hasConcept C160448771 @default.
• W2028505686 hasConcept C170493617 @default.
• W2028505686 hasConcept C171779818 @default.
• W2028505686 hasConcept C195687474 @default.
• W2028505686 hasConcept C198677920 @default.
• W2028505686 hasConcept C203014093 @default.
• W2028505686 hasConcept C2776914184 @default.
• W2028505686 hasConcept C2779170986 @default.
• W2028505686 hasConcept C53122370 @default.
• W2028505686 hasConcept C553184892 @default.
• W2028505686 hasConcept C55493867 @default.
• W2028505686 hasConcept C86803240 @default.
• W2028505686 hasConcept C99971728 @default.
• W2028505686 hasConceptScore W2028505686C104317684 @default.
• W2028505686 hasConceptScore W2028505686C127561419 @default.
• W2028505686 hasConceptScore W2028505686C160448771 @default.
• W2028505686 hasConceptScore W2028505686C170493617 @default.
• W2028505686 hasConceptScore W2028505686C171779818 @default.
• W2028505686 hasConceptScore W2028505686C195687474 @default.
• W2028505686 hasConceptScore W2028505686C198677920 @default.
• W2028505686 hasConceptScore W2028505686C203014093 @default.
• W2028505686 hasConceptScore W2028505686C2776914184 @default.
• W2028505686 hasConceptScore W2028505686C2779170986 @default.
• W2028505686 hasConceptScore W2028505686C53122370 @default.
• W2028505686 hasConceptScore W2028505686C553184892 @default.
• W2028505686 hasConceptScore W2028505686C55493867 @default.
• W2028505686 hasConceptScore W2028505686C86803240 @default.
• W2028505686 hasConceptScore W2028505686C99971728 @default.
• W2028505686 hasIssue "1-2" @default.
• W2028505686 hasLocation W20285056861 @default.
• W2028505686 hasLocation W20285056862 @default.
• W2028505686 hasLocation W20285056863 @default.
• W2028505686 hasOpenAccess W2028505686 @default.
• W2028505686 hasPrimaryLocation W20285056861 @default.
• W2028505686 hasRelatedWork W1925520508 @default.
• W2028505686 hasRelatedWork W1967489534 @default.
• W2028505686 hasRelatedWork W1983358766 @default.
• W2028505686 hasRelatedWork W2028505686 @default.
• W2028505686 hasRelatedWork W2034777534 @default.

• next