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- W2028537675 abstract "In this work we report a detailed characterization of the metallochromic Zincon. Zincon forms complexes with Zn2+ and Cu2+, producing change in colour; the complexes with Fe2+, Mn2+ and Ca2+ cause the bleaching of the Zincon solutions. Mg2+ does not interact with Zincon nor does it change its spectral characteristics. The presence of Ca2+ and Mg2+ does not interface with the spectral characteristics of the Zn-Zincon complex. The Kd, Ks and Δϵ values for the complexes were determined. The Δϵ values were very high, making this spectrophotometric method very sensitive. The complexes Zn-Zincon is fully reversible; however, the complex Cu-Zincon in partially reversible. The free-Zincon, and the complexes Zn-Zincon and Cu-Zincon, does not partition into organic solvents, does not permeate liposome membrane, and neither does it interact with biological membranes. All these characteristics make the metallochronic Zincon useful in biological systems." @default.
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- W2028537675 date "1990-09-01" @default.
- W2028537675 modified "2023-09-27" @default.
- W2028537675 title "Determination of the physicochemical constants and spectrophotometric characteristics of the metallochromic Zincon and its potential use in biological systems" @default.
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- W2028537675 doi "https://doi.org/10.1016/0165-022x(90)90013-3" @default.
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