FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028542896> ?p ?o ?g. }

• W2028542896 endingPage "130" @default.
• W2028542896 startingPage "126" @default.
• W2028542896 abstract "Human whole skin was labeled for 24 h with [6-3H]-glucosamine in organ culture and epidermis, dermis and culture medium were separately analyzed for the molecular mass and content of the [3H]-labeled hyaluronan (HA). Gel filtration on Sephacryl S-1000 of HA purified by HPLC showed a large proportion of the newly synthesized HA to be of a very high molecular mass (greater than 2 X 10(6) Da) in both epidermis and dermis, whereas HA in the medium was of a smaller size. After 24 h chase, most of the high molecular mass HA, and 42-48% of total labeled HA disappeared from both tissue compartments. The size of labeled HA recovered in the chase media was further reduced but the content roughly corresponded to that lost from tissue. The amount of unlabeled HA was not significantly altered in epidermis, whereas in dermis it was reduced to about 10% of the initial values during 5-d culture. The results demonstrate that HA of both epidermis and dermis is synthesized as a very high molecular mass compound but rapidly undergoes a limited degradation into large fragments. The fragmentation of HA is suggested to enhance its diffusion from the tissues, particularly dermis." @default.
• W2028542896 created "2016-06-24" @default.
• W2028542896 creator A5024772304 @default.
• W2028542896 creator A5031933716 @default.
• W2028542896 creator A5054865705 @default.
• W2028542896 creator A5088605616 @default.
• W2028542896 date "1991-07-01" @default.
• W2028542896 modified "2023-09-26" @default.
• W2028542896 title "Degradation of Newly Synthesized High Molecular Mass Hyaluronan in the Epidermal and Dermal Compartments of Human Skin in Organ Culture" @default.
• W2028542896 cites W128396195 @default.
• W2028542896 cites W1468484400 @default.
• W2028542896 cites W1510123979 @default.
• W2028542896 cites W1519926076 @default.
• W2028542896 cites W1529206780 @default.
• W2028542896 cites W1539353994 @default.
• W2028542896 cites W1583037972 @default.
• W2028542896 cites W1612118779 @default.
• W2028542896 cites W1779148953 @default.
• W2028542896 cites W1817704205 @default.
• W2028542896 cites W1968018178 @default.
• W2028542896 cites W2003390679 @default.
• W2028542896 cites W2004749193 @default.
• W2028542896 cites W2011152807 @default.
• W2028542896 cites W2013018835 @default.
• W2028542896 cites W2018106981 @default.
• W2028542896 cites W2024910769 @default.
• W2028542896 cites W2027052280 @default.
• W2028542896 cites W2033867292 @default.
• W2028542896 cites W2048419780 @default.
• W2028542896 cites W2054060446 @default.
• W2028542896 cites W2061095488 @default.
• W2028542896 cites W2066800001 @default.
• W2028542896 cites W2067792814 @default.
• W2028542896 cites W2069762354 @default.
• W2028542896 cites W2071167287 @default.
• W2028542896 cites W2079784375 @default.
• W2028542896 cites W2100881010 @default.
• W2028542896 cites W2129863070 @default.
• W2028542896 cites W2134446953 @default.
• W2028542896 cites W2146694145 @default.
• W2028542896 cites W2152797872 @default.
• W2028542896 cites W2342373299 @default.
• W2028542896 cites W2402578672 @default.
• W2028542896 cites W2413464413 @default.
• W2028542896 doi "https://doi.org/10.1111/1523-1747.ep12478553" @default.
• W2028542896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2056182" @default.
• W2028542896 hasPublicationYear "1991" @default.
• W2028542896 type Work @default.
• W2028542896 sameAs 2028542896 @default.
• W2028542896 citedByCount "142" @default.
• W2028542896 countsByYear W20285428962012 @default.
• W2028542896 countsByYear W20285428962013 @default.
• W2028542896 countsByYear W20285428962014 @default.
• W2028542896 countsByYear W20285428962015 @default.
• W2028542896 countsByYear W20285428962016 @default.
• W2028542896 countsByYear W20285428962017 @default.
• W2028542896 countsByYear W20285428962018 @default.
• W2028542896 countsByYear W20285428962019 @default.
• W2028542896 countsByYear W20285428962020 @default.
• W2028542896 countsByYear W20285428962021 @default.
• W2028542896 countsByYear W20285428962022 @default.
• W2028542896 countsByYear W20285428962023 @default.
• W2028542896 crossrefType "journal-article" @default.
• W2028542896 hasAuthorship W2028542896A5024772304 @default.
• W2028542896 hasAuthorship W2028542896A5031933716 @default.
• W2028542896 hasAuthorship W2028542896A5054865705 @default.
• W2028542896 hasAuthorship W2028542896A5088605616 @default.
• W2028542896 hasConcept C105702510 @default.
• W2028542896 hasConcept C153911025 @default.
• W2028542896 hasConcept C181199279 @default.
• W2028542896 hasConcept C185592680 @default.
• W2028542896 hasConcept C18903297 @default.
• W2028542896 hasConcept C191015642 @default.
• W2028542896 hasConcept C202751555 @default.
• W2028542896 hasConcept C2776458125 @default.
• W2028542896 hasConcept C2777459323 @default.
• W2028542896 hasConcept C2777624698 @default.
• W2028542896 hasConcept C2778125326 @default.
• W2028542896 hasConcept C28483552 @default.
• W2028542896 hasConcept C54355233 @default.
• W2028542896 hasConcept C55493867 @default.
• W2028542896 hasConcept C58121356 @default.
• W2028542896 hasConcept C86803240 @default.
• W2028542896 hasConceptScore W2028542896C105702510 @default.
• W2028542896 hasConceptScore W2028542896C153911025 @default.
• W2028542896 hasConceptScore W2028542896C181199279 @default.
• W2028542896 hasConceptScore W2028542896C185592680 @default.
• W2028542896 hasConceptScore W2028542896C18903297 @default.
• W2028542896 hasConceptScore W2028542896C191015642 @default.
• W2028542896 hasConceptScore W2028542896C202751555 @default.
• W2028542896 hasConceptScore W2028542896C2776458125 @default.
• W2028542896 hasConceptScore W2028542896C2777459323 @default.
• W2028542896 hasConceptScore W2028542896C2777624698 @default.
• W2028542896 hasConceptScore W2028542896C2778125326 @default.
• W2028542896 hasConceptScore W2028542896C28483552 @default.
• W2028542896 hasConceptScore W2028542896C54355233 @default.
• W2028542896 hasConceptScore W2028542896C55493867 @default.
• W2028542896 hasConceptScore W2028542896C58121356 @default.

• next