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- W2028543821 abstract "Anti-idiotypic antibodies were obtained from New Zealand White rabbits injected with affinity-purified rabbit anti-TrpR antibodies. In gel mobility shift studies, such immunoglobulin preparations were shown to contain one or more species able to form specific complexes with DNA molecules bearing a trp operator. In competitive ELISA assays, the binding of anti-idiotypic antibodies to operator-bearing DNA was reversed by TrpR. The demonstration that the immune repertoire contains information for operator-specific DNA-binding proteins may be relevant to the etiology of certain autoimmune diseases." @default.
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- W2028543821 date "1999-10-01" @default.
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- W2028543821 title "Antigen Mimicry by Anti-idiotypic Antibodies: Study of Interactions between Complementary Surfaces in Macromolecules" @default.
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- W2028543821 doi "https://doi.org/10.1006/meth.1999.0859" @default.
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