FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028608038> ?p ?o ?g. }

• W2028608038 endingPage "888" @default.
• W2028608038 startingPage "882" @default.
• W2028608038 abstract "1. Inhibition of human polymorphonuclear leucocyte (PMN) function by adenosine was studied with respect to effects of adenosine on intracellular cyclic AMP and calcium during the PMN respiratory burst. 2. The adenosine analogue 5'-N-ethylcarboxamide-adenosine (NECA) and L-N6-phenyl-isopropyl-adenosine (L-PIA) inhibited PMN oxygen metabolite generation with relative potencies (NECA greater than adenosine greater than L-PIA) characteristic of an A2 receptor. 3. The respiratory burst was inhibited by adenosine when PMN were activated by calcium ionophore or chemotactic peptide but not when cells where activated by oleoyl-acetyl-glycerol (OAG). 4. Adenosine increased intracellular cyclic AMP during the PMN respiratory burst regardless of whether cells were stimulated by ionophore, chemotactic peptide or OAG. 5. To determine whether the differences in cell inhibition by adenosine were related to differences in intracellular calcium mobilization by each activating agent, calcium was evaluated with the fluorescent probe, indo-1. Adenosine suppressed the increase in intracellular calcium following PMN activation by calcium ionophore or chemotactic peptide. In contrast, calcium did not increase in PMN activated by OAG and adenosine did not affect intracellular calcium changes following this stimulus. 6. These results demonstrate that physiological concentrations of adenosine inhibit the PMN respiratory burst in association with an increase in intracellular cyclic AMP and reduction of intracellular calcium." @default.
• W2028608038 created "2016-06-24" @default.
• W2028608038 creator A5065053109 @default.
• W2028608038 creator A5078690248 @default.
• W2028608038 date "1989-07-01" @default.
• W2028608038 modified "2023-09-27" @default.
• W2028608038 title "Effects of adenosine on polymorphonuclear leucocyte function, cyclic 3′:5′-adenosine monophosphate, and intracellular calcium" @default.
• W2028608038 cites W1486575542 @default.
• W2028608038 cites W1557673784 @default.
• W2028608038 cites W1874936548 @default.
• W2028608038 cites W1936333617 @default.
• W2028608038 cites W1944466586 @default.
• W2028608038 cites W1963941498 @default.
• W2028608038 cites W1965340455 @default.
• W2028608038 cites W1978786657 @default.
• W2028608038 cites W1983386883 @default.
• W2028608038 cites W1996024251 @default.
• W2028608038 cites W1996466550 @default.
• W2028608038 cites W1998490733 @default.
• W2028608038 cites W2002432624 @default.
• W2028608038 cites W2007462827 @default.
• W2028608038 cites W2013205823 @default.
• W2028608038 cites W2014272883 @default.
• W2028608038 cites W2019683392 @default.
• W2028608038 cites W2026222135 @default.
• W2028608038 cites W2040571145 @default.
• W2028608038 cites W2041993762 @default.
• W2028608038 cites W2044255707 @default.
• W2028608038 cites W2049856962 @default.
• W2028608038 cites W2065866162 @default.
• W2028608038 cites W2134142368 @default.
• W2028608038 cites W2141260882 @default.
• W2028608038 cites W2146927479 @default.
• W2028608038 cites W2161102001 @default.
• W2028608038 cites W2273482247 @default.
• W2028608038 cites W2409904090 @default.
• W2028608038 cites W2412189132 @default.
• W2028608038 cites W2419099743 @default.
• W2028608038 cites W3023990415 @default.
• W2028608038 doi "https://doi.org/10.1111/j.1476-5381.1989.tb12028.x" @default.
• W2028608038 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1854560" @default.
• W2028608038 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2547490" @default.
• W2028608038 hasPublicationYear "1989" @default.
• W2028608038 type Work @default.
• W2028608038 sameAs 2028608038 @default.
• W2028608038 citedByCount "32" @default.
• W2028608038 countsByYear W20286080382013 @default.
• W2028608038 countsByYear W20286080382014 @default.
• W2028608038 crossrefType "journal-article" @default.
• W2028608038 hasAuthorship W2028608038A5065053109 @default.
• W2028608038 hasAuthorship W2028608038A5078690248 @default.
• W2028608038 hasBestOaLocation W20286080382 @default.
• W2028608038 hasConcept C126322002 @default.
• W2028608038 hasConcept C134018914 @default.
• W2028608038 hasConcept C170493617 @default.
• W2028608038 hasConcept C181080969 @default.
• W2028608038 hasConcept C181199279 @default.
• W2028608038 hasConcept C185592680 @default.
• W2028608038 hasConcept C2776991684 @default.
• W2028608038 hasConcept C2778470358 @default.
• W2028608038 hasConcept C2778938600 @default.
• W2028608038 hasConcept C519063684 @default.
• W2028608038 hasConcept C55493867 @default.
• W2028608038 hasConcept C67907053 @default.
• W2028608038 hasConcept C71924100 @default.
• W2028608038 hasConcept C79879829 @default.
• W2028608038 hasConcept C86803240 @default.
• W2028608038 hasConcept C98539663 @default.
• W2028608038 hasConceptScore W2028608038C126322002 @default.
• W2028608038 hasConceptScore W2028608038C134018914 @default.
• W2028608038 hasConceptScore W2028608038C170493617 @default.
• W2028608038 hasConceptScore W2028608038C181080969 @default.
• W2028608038 hasConceptScore W2028608038C181199279 @default.
• W2028608038 hasConceptScore W2028608038C185592680 @default.
• W2028608038 hasConceptScore W2028608038C2776991684 @default.
• W2028608038 hasConceptScore W2028608038C2778470358 @default.
• W2028608038 hasConceptScore W2028608038C2778938600 @default.
• W2028608038 hasConceptScore W2028608038C519063684 @default.
• W2028608038 hasConceptScore W2028608038C55493867 @default.
• W2028608038 hasConceptScore W2028608038C67907053 @default.
• W2028608038 hasConceptScore W2028608038C71924100 @default.
• W2028608038 hasConceptScore W2028608038C79879829 @default.
• W2028608038 hasConceptScore W2028608038C86803240 @default.
• W2028608038 hasConceptScore W2028608038C98539663 @default.
• W2028608038 hasIssue "3" @default.
• W2028608038 hasLocation W20286080381 @default.
• W2028608038 hasLocation W20286080382 @default.
• W2028608038 hasLocation W20286080383 @default.
• W2028608038 hasLocation W20286080384 @default.
• W2028608038 hasOpenAccess W2028608038 @default.
• W2028608038 hasPrimaryLocation W20286080381 @default.
• W2028608038 hasRelatedWork W1929914845 @default.
• W2028608038 hasRelatedWork W1988001779 @default.
• W2028608038 hasRelatedWork W2010760062 @default.
• W2028608038 hasRelatedWork W2017770252 @default.
• W2028608038 hasRelatedWork W2026105695 @default.
• W2028608038 hasRelatedWork W2031470785 @default.
• W2028608038 hasRelatedWork W2043421191 @default.

• next