FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028705328> ?p ?o ?g. }

• W2028705328 endingPage "46" @default.
• W2028705328 startingPage "37" @default.
• W2028705328 abstract "Summary Perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) directed against cytoplasmic proteins of neutrophils have been studied extensively in patients with systemic vasculitides. Recent data indicate that antineutrophil antibodies in sera from patients with chronic inflammatory bowel diseases (IBD) or autoimmune liver disorders, currently called ‘atypical p-ANCA’, recognize a nuclear target antigen, rendering the term ‘ANCA’ inaccurate. Specific microscopic criteria to distinguish atypical p-ANCA from p-ANCA are lacking. We used planar and confocal laser scanning indirect immunofluorescence microscopy to examine the labelling characteristics of ethanol-, methanol- and formaldehyde-fixed neutrophils by antineutrophil antibodies in 153 serum samples from patients with IBD, autoimmune liver disorders, systemic vasculitides or healthy blood donors. On ethanol- or methanol-fixed neutrophils, multiple intranuclear fluorescent foci together with either a rim-like peripheral nuclear staining (‘type A’) or a combined cytoplasmic and peripheral nuclear staining (‘type B’) was noted exclusively with atypical p-ANCA in sera from patients with IBD or autoimmune liver disorders. Intranuclear foci, which probably corresponded to invaginations of the nuclear envelope, were not labelled by p-ANCA from patients with microscopic polyangiitis or cytoplasmic ANCA (c-ANCA) from patients with Wegener's granulomatosis. On formaldehyde-fixed neutrophils, atypical p-ANCA gave a fine rim-like staining of the nuclear periphery, whereas ANCA diffusely labelled the cytoplasm. To distinguish reliably between the patterns produced by atypical p-ANCA or p-ANCA, particularly p-ANCA, careful indirect immunofluorescence microscopy on ethanol- as well as on formaldehyde-fixed neutrophils is necessary, with particular emphasis on the presence of multiple intranuclear fluorescent foci." @default.
• W2028705328 created "2016-06-24" @default.
• W2028705328 creator A5013739083 @default.
• W2028705328 creator A5025623640 @default.
• W2028705328 creator A5058633927 @default.
• W2028705328 creator A5070567316 @default.
• W2028705328 creator A5071188846 @default.
• W2028705328 date "2001-10-01" @default.
• W2028705328 modified "2023-10-15" @default.
• W2028705328 title "Differentiation of antineutrophil nuclear antibodies in inflammatory bowel and autoimmune liver diseases from antineutrophil cytoplasmic antibodies (p-ANCA) using immunofluorescence microscopy" @default.
• W2028705328 cites W1680550889 @default.
• W2028705328 cites W1744504318 @default.
• W2028705328 cites W1965911418 @default.
• W2028705328 cites W1991590050 @default.
• W2028705328 cites W1996171052 @default.
• W2028705328 cites W1996412256 @default.
• W2028705328 cites W1996871347 @default.
• W2028705328 cites W2007715568 @default.
• W2028705328 cites W2011504371 @default.
• W2028705328 cites W2011818737 @default.
• W2028705328 cites W2013190912 @default.
• W2028705328 cites W2015500098 @default.
• W2028705328 cites W2032686363 @default.
• W2028705328 cites W2039582264 @default.
• W2028705328 cites W2046653318 @default.
• W2028705328 cites W2048714549 @default.
• W2028705328 cites W2052094741 @default.
• W2028705328 cites W2062597287 @default.
• W2028705328 cites W2067360083 @default.
• W2028705328 cites W2083446756 @default.
• W2028705328 cites W2107428250 @default.
• W2028705328 cites W2109943932 @default.
• W2028705328 cites W2116600340 @default.
• W2028705328 cites W2122336053 @default.
• W2028705328 cites W2125373019 @default.
• W2028705328 cites W2140288345 @default.
• W2028705328 cites W2141175809 @default.
• W2028705328 cites W2154267823 @default.
• W2028705328 cites W2162485461 @default.
• W2028705328 cites W2162725007 @default.
• W2028705328 cites W2317186316 @default.
• W2028705328 cites W2332003183 @default.
• W2028705328 cites W2435997465 @default.
• W2028705328 doi "https://doi.org/10.1046/j.1365-2249.2001.01649.x" @default.
• W2028705328 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1906166" @default.
• W2028705328 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11678897" @default.
• W2028705328 hasPublicationYear "2001" @default.
• W2028705328 type Work @default.
• W2028705328 sameAs 2028705328 @default.
• W2028705328 citedByCount "62" @default.
• W2028705328 countsByYear W20287053282012 @default.
• W2028705328 countsByYear W20287053282013 @default.
• W2028705328 countsByYear W20287053282014 @default.
• W2028705328 countsByYear W20287053282015 @default.
• W2028705328 countsByYear W20287053282016 @default.
• W2028705328 countsByYear W20287053282017 @default.
• W2028705328 countsByYear W20287053282018 @default.
• W2028705328 countsByYear W20287053282019 @default.
• W2028705328 countsByYear W20287053282021 @default.
• W2028705328 countsByYear W20287053282022 @default.
• W2028705328 countsByYear W20287053282023 @default.
• W2028705328 crossrefType "journal-article" @default.
• W2028705328 hasAuthorship W2028705328A5013739083 @default.
• W2028705328 hasAuthorship W2028705328A5025623640 @default.
• W2028705328 hasAuthorship W2028705328A5058633927 @default.
• W2028705328 hasAuthorship W2028705328A5070567316 @default.
• W2028705328 hasAuthorship W2028705328A5071188846 @default.
• W2028705328 hasBestOaLocation W20287053282 @default.
• W2028705328 hasConcept C142724271 @default.
• W2028705328 hasConcept C159654299 @default.
• W2028705328 hasConcept C163764329 @default.
• W2028705328 hasConcept C203014093 @default.
• W2028705328 hasConcept C24040308 @default.
• W2028705328 hasConcept C2776015282 @default.
• W2028705328 hasConcept C2778236600 @default.
• W2028705328 hasConcept C2778260677 @default.
• W2028705328 hasConcept C2779134260 @default.
• W2028705328 hasConcept C71924100 @default.
• W2028705328 hasConceptScore W2028705328C142724271 @default.
• W2028705328 hasConceptScore W2028705328C159654299 @default.
• W2028705328 hasConceptScore W2028705328C163764329 @default.
• W2028705328 hasConceptScore W2028705328C203014093 @default.
• W2028705328 hasConceptScore W2028705328C24040308 @default.
• W2028705328 hasConceptScore W2028705328C2776015282 @default.
• W2028705328 hasConceptScore W2028705328C2778236600 @default.
• W2028705328 hasConceptScore W2028705328C2778260677 @default.
• W2028705328 hasConceptScore W2028705328C2779134260 @default.
• W2028705328 hasConceptScore W2028705328C71924100 @default.
• W2028705328 hasIssue "1" @default.
• W2028705328 hasLocation W20287053281 @default.
• W2028705328 hasLocation W20287053282 @default.
• W2028705328 hasLocation W20287053283 @default.
• W2028705328 hasOpenAccess W2028705328 @default.
• W2028705328 hasPrimaryLocation W20287053281 @default.
• W2028705328 hasRelatedWork W179552849 @default.
• W2028705328 hasRelatedWork W2070931144 @default.
• W2028705328 hasRelatedWork W2079913949 @default.
• W2028705328 hasRelatedWork W2162386649 @default.

• next