FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028741060> ?p ?o ?g. }

• W2028741060 endingPage "152" @default.
• W2028741060 startingPage "142" @default.
• W2028741060 abstract "GABA(A) receptors have important physiological functions, as revealed by pharmacological studies and experiments involving gene-targeted mouse models, and are the target of widely used drugs such as the benzodiazepines. In this review, we are summarizing current knowledge about the function of α2-containing GABA(A) receptors, a receptor subtype representing approximately 15-20% of all GABA(A) receptors. This receptor subtype mediates anxiolytic-like, reward-enhancing, and antihyperalgesic actions of diazepam, and has antidepressant-like properties. Secondary insufficiency of α2-containing GABA(A) receptors has been postulated to play a role in the pathogenesis of schizophrenia, and may be involved in cognitive impairment in other disorders. Moreover, polymorphisms in the GABRA2 gene encoding the GABA(A) receptor α2 subunit have been found to be linked to chronic alcohol dependence and to polydrug abuse. Thus, α2-containing GABA(A) receptors are involved in the regulation and/or modulation of emotional behaviors and of chronic pain, and appear to be a valid target for novel therapeutic approaches for the treatment of anxiety, depression, schizophrenia and chronic pain." @default.
• W2028741060 created "2016-06-24" @default.
• W2028741060 creator A5025445381 @default.
• W2028741060 creator A5036255755 @default.
• W2028741060 creator A5049466259 @default.
• W2028741060 date "2012-11-01" @default.
• W2028741060 modified "2023-10-02" @default.
• W2028741060 title "α2-containing GABAA receptors: A target for the development of novel treatment strategies for CNS disorders" @default.
• W2028741060 cites W1582906362 @default.
• W2028741060 cites W1602497443 @default.
• W2028741060 cites W1802854603 @default.
• W2028741060 cites W1965334496 @default.
• W2028741060 cites W1965623485 @default.
• W2028741060 cites W1966479610 @default.
• W2028741060 cites W1968479246 @default.
• W2028741060 cites W1971016878 @default.
• W2028741060 cites W1973651679 @default.
• W2028741060 cites W1975516199 @default.
• W2028741060 cites W1978493649 @default.
• W2028741060 cites W1981049931 @default.
• W2028741060 cites W1987472752 @default.
• W2028741060 cites W1987709429 @default.
• W2028741060 cites W1991475702 @default.
• W2028741060 cites W1997345848 @default.
• W2028741060 cites W2001619275 @default.
• W2028741060 cites W2008027377 @default.
• W2028741060 cites W2009299070 @default.
• W2028741060 cites W2011606970 @default.
• W2028741060 cites W2012446274 @default.
• W2028741060 cites W2013502079 @default.
• W2028741060 cites W2013775967 @default.
• W2028741060 cites W2015488490 @default.
• W2028741060 cites W2015592587 @default.
• W2028741060 cites W2016897420 @default.
• W2028741060 cites W2021553637 @default.
• W2028741060 cites W2022809683 @default.
• W2028741060 cites W2024324079 @default.
• W2028741060 cites W2025287814 @default.
• W2028741060 cites W2028283774 @default.
• W2028741060 cites W2029465256 @default.
• W2028741060 cites W2030154165 @default.
• W2028741060 cites W2031435056 @default.
• W2028741060 cites W2031673474 @default.
• W2028741060 cites W2032093027 @default.
• W2028741060 cites W2034176143 @default.
• W2028741060 cites W2035027696 @default.
• W2028741060 cites W2035055982 @default.
• W2028741060 cites W2036467434 @default.
• W2028741060 cites W2044651421 @default.
• W2028741060 cites W2045221743 @default.
• W2028741060 cites W2046047992 @default.
• W2028741060 cites W2046456472 @default.
• W2028741060 cites W2047801483 @default.
• W2028741060 cites W2049053766 @default.
• W2028741060 cites W2050917344 @default.
• W2028741060 cites W2051758054 @default.
• W2028741060 cites W2052511485 @default.
• W2028741060 cites W2053084684 @default.
• W2028741060 cites W2054931722 @default.
• W2028741060 cites W2056277972 @default.
• W2028741060 cites W2056548197 @default.
• W2028741060 cites W2058355900 @default.
• W2028741060 cites W2060890501 @default.
• W2028741060 cites W2065692979 @default.
• W2028741060 cites W2075895907 @default.
• W2028741060 cites W2080590571 @default.
• W2028741060 cites W2083623577 @default.
• W2028741060 cites W2084539395 @default.
• W2028741060 cites W2087346597 @default.
• W2028741060 cites W2088403668 @default.
• W2028741060 cites W2089184509 @default.
• W2028741060 cites W2089912569 @default.
• W2028741060 cites W2090407373 @default.
• W2028741060 cites W2091712128 @default.
• W2028741060 cites W2093440623 @default.
• W2028741060 cites W2101896575 @default.
• W2028741060 cites W2102092558 @default.
• W2028741060 cites W2102429943 @default.
• W2028741060 cites W2105878094 @default.
• W2028741060 cites W2106257034 @default.
• W2028741060 cites W2106952460 @default.
• W2028741060 cites W2108610913 @default.
• W2028741060 cites W2114079319 @default.
• W2028741060 cites W2116251480 @default.
• W2028741060 cites W2117231835 @default.
• W2028741060 cites W2118195917 @default.
• W2028741060 cites W2118717560 @default.
• W2028741060 cites W2121060688 @default.
• W2028741060 cites W2121237571 @default.
• W2028741060 cites W2126143811 @default.
• W2028741060 cites W2127385137 @default.
• W2028741060 cites W2133217404 @default.
• W2028741060 cites W2133458388 @default.
• W2028741060 cites W2136125607 @default.
• W2028741060 cites W2137471600 @default.
• W2028741060 cites W2143086898 @default.
• W2028741060 cites W2151414518 @default.
• W2028741060 cites W2162515150 @default.

• next