FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028767568> ?p ?o ?g. }

• W2028767568 endingPage "841" @default.
• W2028767568 startingPage "837" @default.
• W2028767568 abstract "We recently reported the use of a chronic dialytic delivery system for intrastriatal administration of quinolinic acid in the rat. This system produces neurodegeneration with some characteristics similar to post mortem brain tissue from Huntington's disease patients, including reduced cytochrome oxidase staining, a decreased number of Nissl-stained neurons, and relative sparing of striatal NADPH-diaphorase containing neurons. The present findings show that chronic dialytic delivery of quinolinic acid also produces a Huntington's disease-like pattern of reduced calbindin and parvalbumin perikaryal immunoreactivity that is reversed in rats allowed four to eight weeks' recovery after cessation of quinolinic acid. Furthermore, cytochrome oxidase staining and the number of Nissl-stained cells were unchanged in the region of transient calbindin and parvalbumin immunoreactive perikaryal staining alterations. These results suggest that changes in calbindin and parvalbumin perikaryal immunoreactivity provide a relatively sensitive measure of quinolinic acid induced neurotoxicity. The reversible nature of reduced perikaryal immunoreactivity suggests a premorbid state of neurotoxicity, possibly marked by cellular redistribution of calbindin and parvalbumin." @default.
• W2028767568 created "2016-06-24" @default.
• W2028767568 creator A5002817065 @default.
• W2028767568 creator A5020240053 @default.
• W2028767568 creator A5026696681 @default.
• W2028767568 creator A5032629344 @default.
• W2028767568 date "1994-06-01" @default.
• W2028767568 modified "2023-10-11" @default.
• W2028767568 title "Chronic intrastriatal quinolinic acid produces reversible changes in perikaryal calbindin and parvalbumin immunoreactivity" @default.
• W2028767568 cites W1523671473 @default.
• W2028767568 cites W1587628722 @default.
• W2028767568 cites W1639407471 @default.
• W2028767568 cites W1905860502 @default.
• W2028767568 cites W1966200464 @default.
• W2028767568 cites W1995345691 @default.
• W2028767568 cites W2004601258 @default.
• W2028767568 cites W2014602692 @default.
• W2028767568 cites W2022777861 @default.
• W2028767568 cites W2036524918 @default.
• W2028767568 cites W2037001268 @default.
• W2028767568 cites W2038917741 @default.
• W2028767568 cites W2045476870 @default.
• W2028767568 cites W2046430928 @default.
• W2028767568 cites W2047452239 @default.
• W2028767568 cites W2053457664 @default.
• W2028767568 cites W2076478145 @default.
• W2028767568 cites W2082249282 @default.
• W2028767568 cites W2086533863 @default.
• W2028767568 cites W2095545913 @default.
• W2028767568 cites W2405475523 @default.
• W2028767568 doi "https://doi.org/10.1016/0306-4522(94)90266-6" @default.
• W2028767568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7523988" @default.
• W2028767568 hasPublicationYear "1994" @default.
• W2028767568 type Work @default.
• W2028767568 sameAs 2028767568 @default.
• W2028767568 citedByCount "26" @default.
• W2028767568 countsByYear W20287675682019 @default.
• W2028767568 crossrefType "journal-article" @default.
• W2028767568 hasAuthorship W2028767568A5002817065 @default.
• W2028767568 hasAuthorship W2028767568A5020240053 @default.
• W2028767568 hasAuthorship W2028767568A5026696681 @default.
• W2028767568 hasAuthorship W2028767568A5032629344 @default.
• W2028767568 hasBestOaLocation W20287675682 @default.
• W2028767568 hasConcept C123249941 @default.
• W2028767568 hasConcept C126322002 @default.
• W2028767568 hasConcept C134018914 @default.
• W2028767568 hasConcept C141547260 @default.
• W2028767568 hasConcept C169760540 @default.
• W2028767568 hasConcept C26265296 @default.
• W2028767568 hasConcept C2776706248 @default.
• W2028767568 hasConcept C2776925932 @default.
• W2028767568 hasConcept C2777896816 @default.
• W2028767568 hasConcept C2779134260 @default.
• W2028767568 hasConcept C2779491297 @default.
• W2028767568 hasConcept C2780358027 @default.
• W2028767568 hasConcept C28859421 @default.
• W2028767568 hasConcept C29730261 @default.
• W2028767568 hasConcept C37753355 @default.
• W2028767568 hasConcept C515207424 @default.
• W2028767568 hasConcept C519063684 @default.
• W2028767568 hasConcept C54355233 @default.
• W2028767568 hasConcept C55493867 @default.
• W2028767568 hasConcept C71924100 @default.
• W2028767568 hasConcept C74864618 @default.
• W2028767568 hasConcept C86803240 @default.
• W2028767568 hasConceptScore W2028767568C123249941 @default.
• W2028767568 hasConceptScore W2028767568C126322002 @default.
• W2028767568 hasConceptScore W2028767568C134018914 @default.
• W2028767568 hasConceptScore W2028767568C141547260 @default.
• W2028767568 hasConceptScore W2028767568C169760540 @default.
• W2028767568 hasConceptScore W2028767568C26265296 @default.
• W2028767568 hasConceptScore W2028767568C2776706248 @default.
• W2028767568 hasConceptScore W2028767568C2776925932 @default.
• W2028767568 hasConceptScore W2028767568C2777896816 @default.
• W2028767568 hasConceptScore W2028767568C2779134260 @default.
• W2028767568 hasConceptScore W2028767568C2779491297 @default.
• W2028767568 hasConceptScore W2028767568C2780358027 @default.
• W2028767568 hasConceptScore W2028767568C28859421 @default.
• W2028767568 hasConceptScore W2028767568C29730261 @default.
• W2028767568 hasConceptScore W2028767568C37753355 @default.
• W2028767568 hasConceptScore W2028767568C515207424 @default.
• W2028767568 hasConceptScore W2028767568C519063684 @default.
• W2028767568 hasConceptScore W2028767568C54355233 @default.
• W2028767568 hasConceptScore W2028767568C55493867 @default.
• W2028767568 hasConceptScore W2028767568C71924100 @default.
• W2028767568 hasConceptScore W2028767568C74864618 @default.
• W2028767568 hasConceptScore W2028767568C86803240 @default.
• W2028767568 hasIssue "4" @default.
• W2028767568 hasLocation W20287675681 @default.
• W2028767568 hasLocation W20287675682 @default.
• W2028767568 hasLocation W20287675683 @default.
• W2028767568 hasOpenAccess W2028767568 @default.
• W2028767568 hasPrimaryLocation W20287675681 @default.
• W2028767568 hasRelatedWork W1993973446 @default.
• W2028767568 hasRelatedWork W2001626568 @default.
• W2028767568 hasRelatedWork W2014380353 @default.
• W2028767568 hasRelatedWork W2021251304 @default.
• W2028767568 hasRelatedWork W2036524918 @default.

• next