Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028805622> ?p ?o ?g. }
- W2028805622 endingPage "293" @default.
- W2028805622 startingPage "280" @default.
- W2028805622 abstract "In the retina, it is not well understood how visual processing depends on AMPA- and NMDA-type glutamate receptors. Here we investigated how these receptors contribute to contrast coding in identified guinea pig ganglion cell types in vitro. NMDA-mediated responses were negligible in ON alpha cells but substantial in OFF alpha and delta cells. OFF delta cell NMDA receptors were composed of GluN2B subunits. Using a novel deconvolution method, we determined the individual contributions of AMPA, NMDA, and inhibitory currents to light responses of each cell type. OFF alpha and delta cells used NMDA receptors for encoding either the full contrast range (alpha), including near-threshold responses, or only a high range (delta). However, contrast sensitivity depended substantially on NMDA receptors only in OFF alpha cells. NMDA receptors contribute to visual contrast coding in a cell-type-specific manner. Certain cell types generate excitatory responses using primarily AMPA receptors or disinhibition." @default.
- W2028805622 created "2016-06-24" @default.
- W2028805622 creator A5001992438 @default.
- W2028805622 creator A5037894693 @default.
- W2028805622 creator A5051436273 @default.
- W2028805622 creator A5088904956 @default.
- W2028805622 date "2010-07-01" @default.
- W2028805622 modified "2023-10-18" @default.
- W2028805622 title "NMDA Receptor Contributions to Visual Contrast Coding" @default.
- W2028805622 cites W1248076745 @default.
- W2028805622 cites W1564717701 @default.
- W2028805622 cites W1581465400 @default.
- W2028805622 cites W1612963976 @default.
- W2028805622 cites W1757146080 @default.
- W2028805622 cites W1781573315 @default.
- W2028805622 cites W1853085112 @default.
- W2028805622 cites W1858043581 @default.
- W2028805622 cites W1920017598 @default.
- W2028805622 cites W1940417817 @default.
- W2028805622 cites W1967349182 @default.
- W2028805622 cites W1970044757 @default.
- W2028805622 cites W1974487245 @default.
- W2028805622 cites W1976476713 @default.
- W2028805622 cites W1984579614 @default.
- W2028805622 cites W1985768427 @default.
- W2028805622 cites W1987771959 @default.
- W2028805622 cites W1991302410 @default.
- W2028805622 cites W1993736839 @default.
- W2028805622 cites W1994868555 @default.
- W2028805622 cites W1995043049 @default.
- W2028805622 cites W1997568797 @default.
- W2028805622 cites W1998347917 @default.
- W2028805622 cites W2015872566 @default.
- W2028805622 cites W2017910024 @default.
- W2028805622 cites W2032977417 @default.
- W2028805622 cites W2035537230 @default.
- W2028805622 cites W2043261639 @default.
- W2028805622 cites W2046297486 @default.
- W2028805622 cites W2046504812 @default.
- W2028805622 cites W2047141148 @default.
- W2028805622 cites W2048367346 @default.
- W2028805622 cites W2051185231 @default.
- W2028805622 cites W2053055036 @default.
- W2028805622 cites W2053980736 @default.
- W2028805622 cites W2054747517 @default.
- W2028805622 cites W2056356727 @default.
- W2028805622 cites W2059571588 @default.
- W2028805622 cites W2059627330 @default.
- W2028805622 cites W2061544984 @default.
- W2028805622 cites W2062665179 @default.
- W2028805622 cites W2068387849 @default.
- W2028805622 cites W2069317420 @default.
- W2028805622 cites W2072491375 @default.
- W2028805622 cites W2075877638 @default.
- W2028805622 cites W2090476414 @default.
- W2028805622 cites W2090923339 @default.
- W2028805622 cites W2100829711 @default.
- W2028805622 cites W2106081121 @default.
- W2028805622 cites W2107339318 @default.
- W2028805622 cites W2108904897 @default.
- W2028805622 cites W2111846174 @default.
- W2028805622 cites W2112730272 @default.
- W2028805622 cites W2115135943 @default.
- W2028805622 cites W2115441910 @default.
- W2028805622 cites W2115857330 @default.
- W2028805622 cites W2120419858 @default.
- W2028805622 cites W2123191391 @default.
- W2028805622 cites W2124934034 @default.
- W2028805622 cites W2133128074 @default.
- W2028805622 cites W2138615044 @default.
- W2028805622 cites W2142965243 @default.
- W2028805622 cites W2150040413 @default.
- W2028805622 cites W2151351318 @default.
- W2028805622 cites W2152938026 @default.
- W2028805622 cites W2164792033 @default.
- W2028805622 cites W2165664498 @default.
- W2028805622 cites W2170749456 @default.
- W2028805622 cites W2171532835 @default.
- W2028805622 cites W2171943613 @default.
- W2028805622 cites W2172073217 @default.
- W2028805622 cites W2179166911 @default.
- W2028805622 cites W2342328537 @default.
- W2028805622 cites W2418317612 @default.
- W2028805622 cites W4296436262 @default.
- W2028805622 doi "https://doi.org/10.1016/j.neuron.2010.06.020" @default.
- W2028805622 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2913150" @default.
- W2028805622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20670835" @default.
- W2028805622 hasPublicationYear "2010" @default.
- W2028805622 type Work @default.
- W2028805622 sameAs 2028805622 @default.
- W2028805622 citedByCount "47" @default.
- W2028805622 countsByYear W20288056222012 @default.
- W2028805622 countsByYear W20288056222013 @default.
- W2028805622 countsByYear W20288056222014 @default.
- W2028805622 countsByYear W20288056222015 @default.
- W2028805622 countsByYear W20288056222016 @default.
- W2028805622 countsByYear W20288056222017 @default.
- W2028805622 countsByYear W20288056222018 @default.