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- W2028842799 abstract "A specific illumination approach has been developed for identification of adenosine triphosphate (ATP)-binding proteins. This strategy utilizes a tandem photoactivatable unit that consists of a diazirine group as a carbene precursor and an o-hydroxycinnamate moiety as a coumarin precursor. The photolysis of diazirine induces a specific cross-link on target proteins and is followed by photoactivation of coumarin generation with a concomitant release of the pre-installed affinity ligand. The ATP, installed with this cross-linker at the γ-position, successfully transferred a coumarin onto ATP-binding proteins using only UV-irradiation." @default.
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- W2028842799 date "2013-10-01" @default.
- W2028842799 modified "2023-09-27" @default.
- W2028842799 title "Affinity-based fluorogenic labeling of ATP-binding proteins with sequential photoactivatable cross-linkers" @default.
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- W2028842799 doi "https://doi.org/10.1016/j.bmcl.2013.08.041" @default.
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