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- W2028843555 abstract "Immunoglobulin G (IgG) was purified by affinity chromatography from the CSF of multiple sclerosis (MS) patients and controls. In MS patients, the IgG fraction contains anti-myelin basic protein (anti-MBP), anti-MBP neutralizing antibody and an antibody which inhibits neutralization of anti-MBP. Anti-MBP was detected in patients with acute relapses, anti-MBP neutralizing antibody was present in patients in clinical remission and the inhibiting antibody was detected in patients with chronically progressing MS. A myelin basic protein antibody cascade could be involved in the mechanism of MS." @default.
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- W2028843555 date "1990-04-01" @default.
- W2028843555 modified "2023-09-24" @default.
- W2028843555 title "A myelin basic protein antibody cascade in purified IgG from cerebrospinal fluid of multiple sclerosis patients" @default.
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- W2028843555 doi "https://doi.org/10.1016/0022-510x(90)90053-p" @default.
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