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• W2028905487 endingPage "644" @default.
• W2028905487 startingPage "638" @default.
• W2028905487 abstract "F-actin is the major component of muscle thin filaments and, more generally, of the microfilaments of the dynamic, multifunctional cytoskeletal systems of nonmuscle eukaryotic cells. Polymeric F-actin is formed by reversible noncovalent self-association of monomeric G-actin. To understand the dynamics of microfilament systems in cells, the dynamics of polymerization of pure actin must be understood. The following model has emerged from recent work. During the polymerization process, adenosine 5'-triphosphate (ATP) that is bound to G-actin is hydrolyzed to adenosine 5'-diphosphate (ADP) that is bound to F-actin. The hydrolysis reaction occurs on the F-actin subsequent to the polymerization reaction in two steps: cleavage of ATP followed by the slower release of inorganic phosphate (Pi). As a result, at high rates of filament growth a transient cap of ATP-actin subunits exists at the ends of elongating filaments, and at steady state a stabilizing cap of ADP.Pi-actin subunits exists at the barbed ends of filaments. Cleavage of ATP results in a highly stable filament with bound ADP.Pi, and release of Pi destabilizes the filament. Thus these two steps of the hydrolytic reaction provide potential mechanisms for regulating the monomer-polymer transition." @default.
• W2028905487 created "2016-06-24" @default.
• W2028905487 creator A5021460730 @default.
• W2028905487 creator A5056320284 @default.
• W2028905487 creator A5091304112 @default.
• W2028905487 date "1987-10-30" @default.
• W2028905487 modified "2023-10-14" @default.
• W2028905487 title "Actin Polymerization and ATP Hydrolysis" @default.
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• W2028905487 cites W1484769338 @default.
• W2028905487 cites W1489297072 @default.
• W2028905487 cites W1495187969 @default.
• W2028905487 cites W1505374435 @default.
• W2028905487 cites W1515742161 @default.
• W2028905487 cites W1536642642 @default.
• W2028905487 cites W1537658354 @default.
• W2028905487 cites W1540455329 @default.
• W2028905487 cites W1566481288 @default.
• W2028905487 cites W1567519192 @default.
• W2028905487 cites W1568637259 @default.
• W2028905487 cites W1569490850 @default.
• W2028905487 cites W1571679969 @default.
• W2028905487 cites W1576318030 @default.
• W2028905487 cites W1580075072 @default.
• W2028905487 cites W1599563939 @default.
• W2028905487 cites W1606080659 @default.
• W2028905487 cites W1678878269 @default.
• W2028905487 cites W1835632918 @default.
• W2028905487 cites W1848811541 @default.
• W2028905487 cites W1914021328 @default.
• W2028905487 cites W1963507186 @default.
• W2028905487 cites W1965404941 @default.
• W2028905487 cites W1977801865 @default.
• W2028905487 cites W1980389907 @default.
• W2028905487 cites W1984318405 @default.
• W2028905487 cites W1987589427 @default.
• W2028905487 cites W1992345201 @default.
• W2028905487 cites W1993485613 @default.
• W2028905487 cites W1998884471 @default.
• W2028905487 cites W2003468593 @default.
• W2028905487 cites W2007592490 @default.
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• W2028905487 cites W2009623058 @default.
• W2028905487 cites W2009819585 @default.
• W2028905487 cites W2015918937 @default.
• W2028905487 cites W2017973534 @default.
• W2028905487 cites W2019721152 @default.
• W2028905487 cites W2022943729 @default.
• W2028905487 cites W2024141074 @default.
• W2028905487 cites W2024153926 @default.
• W2028905487 cites W2024288413 @default.
• W2028905487 cites W2038156299 @default.
• W2028905487 cites W2038444354 @default.
• W2028905487 cites W2044540369 @default.
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• W2028905487 cites W2046060747 @default.
• W2028905487 cites W2047434131 @default.
• W2028905487 cites W2047579047 @default.
• W2028905487 cites W2049148686 @default.
• W2028905487 cites W2051165421 @default.
• W2028905487 cites W2054639242 @default.
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• W2028905487 cites W2082026346 @default.
• W2028905487 cites W2084051721 @default.
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• W2028905487 cites W2088677348 @default.
• W2028905487 cites W2088727427 @default.
• W2028905487 cites W2103446130 @default.
• W2028905487 cites W2109715046 @default.
• W2028905487 cites W2110596117 @default.
• W2028905487 cites W2115876454 @default.
• W2028905487 cites W2131864418 @default.
• W2028905487 cites W2132968948 @default.
• W2028905487 cites W2135977869 @default.
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• W2028905487 cites W2171956751 @default.
• W2028905487 cites W2172673878 @default.
• W2028905487 cites W2172852338 @default.
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• W2028905487 doi "https://doi.org/10.1126/science.3672117" @default.
• W2028905487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3672117" @default.
• W2028905487 hasPublicationYear "1987" @default.
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