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- W2028941363 abstract "It has recently been discovered that the Drosophila β-amyloid protein precursor like (Appl) gene, the ortholog of the human β-Amyloid Precursor Protein (APP) gene, is transcriptionally activated by receptor tyrosine kinase activity that involves Ras/MAPK signaling in vivo. This regulation is specifically controlled in photoreceptor neurons of the Drosophila retina. This suggests that some cases of Alzheimer disease, those which have been associated with high expression of the APP gene, may involve Ras signal transduction." @default.
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- W2028941363 date "2013-07-01" @default.
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- W2028941363 title "Rassignal triggersβ-Amyloid Precursor Protein(APP) expression" @default.
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- W2028941363 doi "https://doi.org/10.4161/sgtp.24768" @default.
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