Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028973387> ?p ?o ?g. }
- W2028973387 endingPage "1288" @default.
- W2028973387 startingPage "1279" @default.
- W2028973387 abstract "H2A.Z is an evolutionarily highly conserved non-allelic variant of histone H2A. H2A.Z and its homologues have been shown to involve in both chromatin silencing and activation. Although much of our knowledge of H2A.Z biological activity has come from studies on its yeast homologue Htz1, H2A.Z appears to have more complex and diverse functions in higher eukaryotes. To investigate the involvement of H2AvD, a Drosophila homologue of mammalian H2A.Z, in mechanisms of conditional activation of facultatively silenced genes, we generated transgenic Drosophila lines expressing H2AvD fused at the C- or N-terminus with the green fluorescent protein (GFP). Using heat shock-induced gene activation and polytene chromosome puff formation as an in vivo model system, we analyzed effects of H2AvD termini modifications on transcription. We found that N-terminally fused GFP inhibited H2AvD acetylation and impaired heat shock-induced puff formation and hsp70 gene activation. Our data suggest that the N-terminal region of H2AvD plays a pivotal role in transcriptional activation and that induction of transiently silenced Drosophila loci associates with increased acetylation of H2AvD." @default.
- W2028973387 created "2016-06-24" @default.
- W2028973387 creator A5003797388 @default.
- W2028973387 creator A5011556096 @default.
- W2028973387 creator A5014742849 @default.
- W2028973387 creator A5025267123 @default.
- W2028973387 creator A5035702067 @default.
- W2028973387 creator A5039509925 @default.
- W2028973387 creator A5049361786 @default.
- W2028973387 creator A5058815783 @default.
- W2028973387 creator A5060983596 @default.
- W2028973387 creator A5061501935 @default.
- W2028973387 creator A5064125582 @default.
- W2028973387 creator A5068311388 @default.
- W2028973387 creator A5082685958 @default.
- W2028973387 creator A5083784015 @default.
- W2028973387 date "2008-11-20" @default.
- W2028973387 modified "2023-10-12" @default.
- W2028973387 title "<i>Retracted:</i>Activation of facultatively silenced<i>Drosophila</i>loci associates with increased acetylation of histone H2AvD" @default.
- W2028973387 cites W1532505992 @default.
- W2028973387 cites W154608328 @default.
- W2028973387 cites W1968987470 @default.
- W2028973387 cites W1976968160 @default.
- W2028973387 cites W1978893041 @default.
- W2028973387 cites W1979187818 @default.
- W2028973387 cites W1979632079 @default.
- W2028973387 cites W1987020026 @default.
- W2028973387 cites W1992555811 @default.
- W2028973387 cites W2003379794 @default.
- W2028973387 cites W2003650751 @default.
- W2028973387 cites W2008308209 @default.
- W2028973387 cites W2029388127 @default.
- W2028973387 cites W2032969093 @default.
- W2028973387 cites W2039564969 @default.
- W2028973387 cites W2041383836 @default.
- W2028973387 cites W2042249135 @default.
- W2028973387 cites W2044681616 @default.
- W2028973387 cites W2065782017 @default.
- W2028973387 cites W2084388180 @default.
- W2028973387 cites W2084509375 @default.
- W2028973387 cites W2093228543 @default.
- W2028973387 cites W2100089916 @default.
- W2028973387 cites W2102901123 @default.
- W2028973387 cites W2110033136 @default.
- W2028973387 cites W2113478190 @default.
- W2028973387 cites W2117100349 @default.
- W2028973387 cites W2128542570 @default.
- W2028973387 cites W2143658931 @default.
- W2028973387 cites W2145924925 @default.
- W2028973387 cites W2146865647 @default.
- W2028973387 cites W2150514867 @default.
- W2028973387 cites W2158747282 @default.
- W2028973387 cites W2158901355 @default.
- W2028973387 cites W2160025279 @default.
- W2028973387 cites W2160345231 @default.
- W2028973387 cites W2164314558 @default.
- W2028973387 doi "https://doi.org/10.1111/j.1365-2443.2008.01244.x" @default.
- W2028973387 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19032341" @default.
- W2028973387 hasPublicationYear "2008" @default.
- W2028973387 type Work @default.
- W2028973387 sameAs 2028973387 @default.
- W2028973387 citedByCount "11" @default.
- W2028973387 countsByYear W20289733872013 @default.
- W2028973387 countsByYear W20289733872014 @default.
- W2028973387 countsByYear W20289733872015 @default.
- W2028973387 countsByYear W20289733872017 @default.
- W2028973387 countsByYear W20289733872021 @default.
- W2028973387 crossrefType "journal-article" @default.
- W2028973387 hasAuthorship W2028973387A5003797388 @default.
- W2028973387 hasAuthorship W2028973387A5011556096 @default.
- W2028973387 hasAuthorship W2028973387A5014742849 @default.
- W2028973387 hasAuthorship W2028973387A5025267123 @default.
- W2028973387 hasAuthorship W2028973387A5035702067 @default.
- W2028973387 hasAuthorship W2028973387A5039509925 @default.
- W2028973387 hasAuthorship W2028973387A5049361786 @default.
- W2028973387 hasAuthorship W2028973387A5058815783 @default.
- W2028973387 hasAuthorship W2028973387A5060983596 @default.
- W2028973387 hasAuthorship W2028973387A5061501935 @default.
- W2028973387 hasAuthorship W2028973387A5064125582 @default.
- W2028973387 hasAuthorship W2028973387A5068311388 @default.
- W2028973387 hasAuthorship W2028973387A5082685958 @default.
- W2028973387 hasAuthorship W2028973387A5083784015 @default.
- W2028973387 hasBestOaLocation W20289733871 @default.
- W2028973387 hasConcept C104317684 @default.
- W2028973387 hasConcept C119056186 @default.
- W2028973387 hasConcept C119157956 @default.
- W2028973387 hasConcept C138885662 @default.
- W2028973387 hasConcept C153911025 @default.
- W2028973387 hasConcept C179926584 @default.
- W2028973387 hasConcept C2780104201 @default.
- W2028973387 hasConcept C41895202 @default.
- W2028973387 hasConcept C51423104 @default.
- W2028973387 hasConcept C54355233 @default.
- W2028973387 hasConcept C64927066 @default.
- W2028973387 hasConcept C83640560 @default.
- W2028973387 hasConcept C86803240 @default.
- W2028973387 hasConcept C95444343 @default.
- W2028973387 hasConceptScore W2028973387C104317684 @default.