Matches in SemOpenAlex for { <https://semopenalex.org/work/W2028987130> ?p ?o ?g. }
- W2028987130 endingPage "1135" @default.
- W2028987130 startingPage "1129" @default.
- W2028987130 abstract "IGF-I and IGF binding protein-3 (IGFBP-3) are essential for growth and maturation of the developing brain.The aim of this study was to evaluate the association between postnatal serum concentrations of IGF-I and IGFBP-3 and brain volumes at term in very preterm infants.Fifty-one infants with a mean (sd) gestational age (GA) of 26.4 (1.9) wk and birth weight (BW) of 888 (288) g were studied, with weekly blood sampling of IGF-I and IGFBP-3 from birth until 35 gestational weeks (GW) and daily calculation of protein and caloric intake. Magnetic resonance images obtained at 40 GW were segmented into total brain, cerebellar, cerebrospinal fluid, gray matter, and unmyelinated white matter volumes.We evaluated brain growth by measuring brain volumes using magnetic resonance imaging.Mean IGF-I concentrations from birth to 35 GW correlated with total brain volume, unmyelinated white matter volume, gray matter volume, and cerebellar volume [r = 0.55 (P < 0.001); r = 0.55 (P < 0.001); r = 0.44 (P = 0.002); and r = 0.58 (P < 0.001), respectively]. Similar correlations were observed for IGFBP-3 concentrations. Correlations remained after adjustment for GA, mean protein and caloric intakes, gender, severe brain damage, and steroid treatment. Protein and caloric intakes were not related to brain volumes. Infants with BW small for GA had lower mean concentrations of IGF-I (P = 0.006) and smaller brain volumes (P = 0.001-0.013) than infants with BW appropriate for GA.Postnatal IGF-I and IGFBP-3 concentrations are positively associated with brain volumes at 40 GW in very preterm infants. Normalization of the IGF-I axis, directly or indirectly, may support normal brain development in very preterm infants." @default.
- W2028987130 created "2016-06-24" @default.
- W2028987130 creator A5013017099 @default.
- W2028987130 creator A5016603204 @default.
- W2028987130 creator A5029925223 @default.
- W2028987130 creator A5041165986 @default.
- W2028987130 creator A5049802907 @default.
- W2028987130 creator A5050308092 @default.
- W2028987130 creator A5051004312 @default.
- W2028987130 creator A5054835375 @default.
- W2028987130 creator A5071645839 @default.
- W2028987130 creator A5084831116 @default.
- W2028987130 date "2011-04-01" @default.
- W2028987130 modified "2023-10-18" @default.
- W2028987130 title "Postnatal Decrease in Circulating Insulin-Like Growth Factor-I and Low Brain Volumes in Very Preterm Infants" @default.
- W2028987130 cites W1572909157 @default.
- W2028987130 cites W1864437270 @default.
- W2028987130 cites W1884170163 @default.
- W2028987130 cites W1932296264 @default.
- W2028987130 cites W1970864607 @default.
- W2028987130 cites W1971120965 @default.
- W2028987130 cites W1971168063 @default.
- W2028987130 cites W1986171491 @default.
- W2028987130 cites W1988964205 @default.
- W2028987130 cites W1993280157 @default.
- W2028987130 cites W1998376780 @default.
- W2028987130 cites W2004286315 @default.
- W2028987130 cites W2007466363 @default.
- W2028987130 cites W2009561775 @default.
- W2028987130 cites W2010363122 @default.
- W2028987130 cites W2017311476 @default.
- W2028987130 cites W2019084238 @default.
- W2028987130 cites W2027260046 @default.
- W2028987130 cites W2031964928 @default.
- W2028987130 cites W2036110820 @default.
- W2028987130 cites W2037908014 @default.
- W2028987130 cites W2044947593 @default.
- W2028987130 cites W2064147974 @default.
- W2028987130 cites W2068304779 @default.
- W2028987130 cites W2077803675 @default.
- W2028987130 cites W2078353486 @default.
- W2028987130 cites W2080386012 @default.
- W2028987130 cites W2105570493 @default.
- W2028987130 cites W2116599722 @default.
- W2028987130 cites W2123852291 @default.
- W2028987130 cites W2130112708 @default.
- W2028987130 cites W2132422110 @default.
- W2028987130 cites W2140190130 @default.
- W2028987130 cites W2151329912 @default.
- W2028987130 cites W2162945322 @default.
- W2028987130 cites W2163124631 @default.
- W2028987130 cites W2170674178 @default.
- W2028987130 cites W2320296534 @default.
- W2028987130 doi "https://doi.org/10.1210/jc.2010-2440" @default.
- W2028987130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21289247" @default.
- W2028987130 hasPublicationYear "2011" @default.
- W2028987130 type Work @default.
- W2028987130 sameAs 2028987130 @default.
- W2028987130 citedByCount "74" @default.
- W2028987130 countsByYear W20289871302012 @default.
- W2028987130 countsByYear W20289871302013 @default.
- W2028987130 countsByYear W20289871302014 @default.
- W2028987130 countsByYear W20289871302015 @default.
- W2028987130 countsByYear W20289871302016 @default.
- W2028987130 countsByYear W20289871302017 @default.
- W2028987130 countsByYear W20289871302018 @default.
- W2028987130 countsByYear W20289871302019 @default.
- W2028987130 countsByYear W20289871302020 @default.
- W2028987130 countsByYear W20289871302021 @default.
- W2028987130 countsByYear W20289871302022 @default.
- W2028987130 countsByYear W20289871302023 @default.
- W2028987130 crossrefType "journal-article" @default.
- W2028987130 hasAuthorship W2028987130A5013017099 @default.
- W2028987130 hasAuthorship W2028987130A5016603204 @default.
- W2028987130 hasAuthorship W2028987130A5029925223 @default.
- W2028987130 hasAuthorship W2028987130A5041165986 @default.
- W2028987130 hasAuthorship W2028987130A5049802907 @default.
- W2028987130 hasAuthorship W2028987130A5050308092 @default.
- W2028987130 hasAuthorship W2028987130A5051004312 @default.
- W2028987130 hasAuthorship W2028987130A5054835375 @default.
- W2028987130 hasAuthorship W2028987130A5071645839 @default.
- W2028987130 hasAuthorship W2028987130A5084831116 @default.
- W2028987130 hasBestOaLocation W20289871301 @default.
- W2028987130 hasConcept C126322002 @default.
- W2028987130 hasConcept C126838900 @default.
- W2028987130 hasConcept C134018914 @default.
- W2028987130 hasConcept C143409427 @default.
- W2028987130 hasConcept C169760540 @default.
- W2028987130 hasConcept C170493617 @default.
- W2028987130 hasConcept C2775960820 @default.
- W2028987130 hasConcept C2778376644 @default.
- W2028987130 hasConcept C2779234561 @default.
- W2028987130 hasConcept C2779651940 @default.
- W2028987130 hasConcept C2779652256 @default.
- W2028987130 hasConcept C2780378035 @default.
- W2028987130 hasConcept C2780689927 @default.
- W2028987130 hasConcept C2781192897 @default.
- W2028987130 hasConcept C2984223407 @default.