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• W2029013553 endingPage "e14685" @default.
• W2029013553 startingPage "e14685" @default.
• W2029013553 abstract "Several components of dairy products have been linked to earlier menarche.This study assessed whether positive associations exist between childhood milk consumption and age at menarche or the likelihood of early menarche (<12 yrs) in a U.S sample. Data derive from the National Health and Nutrition Examination Survey (NHANES) 1999-2004. Two samples were utilized: 2657 women age 20-49 yrs and 1008 girls age 9-12 yrs. In regression analysis, a weak negative relationship was found between frequency of milk consumption at 5-12 yrs and age at menarche (daily milk intake β = -0.32, P<0.10; sometimes/variable milk intake β = -0.38, P<0.06, each compared to intake rarely/never). Cox regression yielded no greater risk of early menarche among those who drank milk sometimes/varied or daily vs. never/rarely (HR: 1.20, P<0.42, HR: 1.25, P<0.23, respectively). Among the 9-12 yr olds, Cox regression indicated that neither total dairy kcal, calcium and protein, nor daily milk intake in the past 30 days contributed to early menarche. Girls in the middle tertile of milk intake had a marginally lower risk of early menarche than those in the highest tertile (HR: 0.6, P<0.06). Those in the lowest tertiles of dairy fat intake had a greater risk of early menarche than those in the highest (HR: 1.5, P<0.05, HR: 1.6, P<0.07, lowest and middle tertile, respectively), while those with the lowest calcium intake had a lower risk of early menarche (HR: 0.6, P<0.05) than those in the highest tertile. These relationships remained after adjusting for overweight or overweight and height percentile; both increased the risk of earlier menarche. Blacks were more likely than Whites to reach menarche early (HR: 1.7, P<0.03), but not after controlling for overweight.There is some evidence that greater milk intake is associated with an increased risk of early menarche, or a lower age at menarche." @default.
• W2029013553 created "2016-06-24" @default.
• W2029013553 creator A5031099106 @default.
• W2029013553 date "2011-02-14" @default.
• W2029013553 modified "2023-10-04" @default.
• W2029013553 title "Milk Intake and Total Dairy Consumption: Associations with Early Menarche in NHANES 1999-2004" @default.
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• W2029013553 doi "https://doi.org/10.1371/journal.pone.0014685" @default.
• W2029013553 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3038976" @default.
• W2029013553 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21347271" @default.
• W2029013553 hasPublicationYear "2011" @default.
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