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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029021649> ?p ?o ?g. }

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• W2029021649 abstract "Some hepatitis B vaccine booster studies have suggested waning of vaccine-induced immunity in adolescents vaccinated starting at birth. Those studies, however, used a pediatric formulation of the hepatitis B vaccine as a booster to detect anamnestic response. We compared adolescents boosted with an adult dose of hepatitis B vaccine with those boosted with a pediatric dose. Among adolescents who had lost protective antibody levels against hepatitis B, a higher proportion had an anamnestic response when boosted with the adult dose (60.0% vs. 43.8%). Thus, higher antigen concentrations may be required to elicit an adequate immune memory response. Despite improved anamnestic response, our study still raises concerns about whether children immunized in early infancy will remain protected from hepatitis B as they age into adulthood." @default.
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• W2029021649 date "2010-04-01" @default.
• W2029021649 modified "2023-09-26" @default.
• W2029021649 title "Improved anamnestic response among adolescents boosted with a higher dose of the hepatitis B vaccine" @default.
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• W2029021649 doi "https://doi.org/10.1016/j.vaccine.2010.01.059" @default.
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