FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029039557> ?p ?o ?g. }

• W2029039557 endingPage "1368" @default.
• W2029039557 startingPage "1362" @default.
• W2029039557 abstract "The optimal treatment of low-stage nonseminomatous germ cell testicular cancer (NSGCT) is controversial. For clinical stage (CS) I NSGCT, retroperitoneal lymph node dissection (RPLND), two cycles of chemotherapy and surveillance are all accepted treatment options. For CS IIA-B, standard treatments include RPLND (+/- adjuvant chemotherapy) and induction chemotherapy (+/- RPLND). The long-term survival rate is >97% for CS I and 95% for CS IIA-B NSGCT, regardless of the treatment received. The risk of retroperitoneal metastasis varies by clinical stage (25-35% for CS I, 65-85% for CS IIA-B), and the presence of lymphovascular invasion and percentage of embryonal carcinoma in the primary tumour. Patients with elevated serum tumour markers (STMs) and adenopathy of >3 cm are at high risk of having occult systemic disease. Compared with chemotherapy, RPLND is associated with a considerably more favourable long-term morbidity profile and is the most effective method for controlling the retroperitoneum. Surveillance is associated with the lowest risk of long-term complications. As such, we favour surveillance for low-risk CS I, induction chemotherapy for those at high risk of systemic disease (elevated STM, adenopathy >3 cm), and RPLND for all others. Modified template dissections reduce the risk of ejaculatory dysfunction, but might increase the risk of local recurrence. Therefore, we favour a full-bilateral template dissection with nerve-sparing in patients with low-stage NSGCT. The therapeutic efficacy of laparoscopic RPLND is not proven and currently should be considered a staging procedure only. Adjuvant chemotherapy after RPLND is typically restricted to patients with pathological stage N2-3 disease." @default.
• W2029039557 created "2016-06-24" @default.
• W2029039557 creator A5001069772 @default.
• W2029039557 creator A5077333954 @default.
• W2029039557 date "2009-10-13" @default.
• W2029039557 modified "2023-10-17" @default.
• W2029039557 title "Surgical management of low-stage nonseminomatous germ cell testicular cancer" @default.
• W2029039557 cites W118559235 @default.
• W2029039557 cites W1584634571 @default.
• W2029039557 cites W170472323 @default.
• W2029039557 cites W174998155 @default.
• W2029039557 cites W1900110139 @default.
• W2029039557 cites W1952048380 @default.
• W2029039557 cites W1966365492 @default.
• W2029039557 cites W1967085745 @default.
• W2029039557 cites W1968178814 @default.
• W2029039557 cites W1977545074 @default.
• W2029039557 cites W1980318009 @default.
• W2029039557 cites W1987316304 @default.
• W2029039557 cites W1989541303 @default.
• W2029039557 cites W1990550229 @default.
• W2029039557 cites W1991220457 @default.
• W2029039557 cites W1991418137 @default.
• W2029039557 cites W1993989236 @default.
• W2029039557 cites W2001672955 @default.
• W2029039557 cites W2003778169 @default.
• W2029039557 cites W2006565654 @default.
• W2029039557 cites W2008323952 @default.
• W2029039557 cites W2021106346 @default.
• W2029039557 cites W2023104616 @default.
• W2029039557 cites W2026102604 @default.
• W2029039557 cites W2028974865 @default.
• W2029039557 cites W2033368464 @default.
• W2029039557 cites W2035023171 @default.
• W2029039557 cites W2040184182 @default.
• W2029039557 cites W2047398804 @default.
• W2029039557 cites W2058961649 @default.
• W2029039557 cites W2065614549 @default.
• W2029039557 cites W2066021065 @default.
• W2029039557 cites W2076172260 @default.
• W2029039557 cites W2080363984 @default.
• W2029039557 cites W2083808201 @default.
• W2029039557 cites W20929017 @default.
• W2029039557 cites W2093853170 @default.
• W2029039557 cites W2107548403 @default.
• W2029039557 cites W2108522817 @default.
• W2029039557 cites W2109175854 @default.
• W2029039557 cites W2109392790 @default.
• W2029039557 cites W2118752091 @default.
• W2029039557 cites W2130803751 @default.
• W2029039557 cites W2131748799 @default.
• W2029039557 cites W2132274239 @default.
• W2029039557 cites W2139472234 @default.
• W2029039557 cites W2141964341 @default.
• W2029039557 cites W2163970298 @default.
• W2029039557 cites W2168522367 @default.
• W2029039557 cites W2169428224 @default.
• W2029039557 cites W2175942611 @default.
• W2029039557 cites W2211078106 @default.
• W2029039557 cites W2220613250 @default.
• W2029039557 cites W2264132604 @default.
• W2029039557 cites W2312985307 @default.
• W2029039557 cites W2325651197 @default.
• W2029039557 cites W2340182039 @default.
• W2029039557 cites W2400462711 @default.
• W2029039557 cites W2405731004 @default.
• W2029039557 cites W2472458074 @default.
• W2029039557 cites W30480392 @default.
• W2029039557 cites W4232182820 @default.
• W2029039557 cites W4319054742 @default.
• W2029039557 cites W4362231427 @default.
• W2029039557 cites W4367435824 @default.
• W2029039557 cites W4375269684 @default.
• W2029039557 cites W57888176 @default.
• W2029039557 cites W2752971847 @default.
• W2029039557 doi "https://doi.org/10.1111/j.1464-410x.2009.08860.x" @default.
• W2029039557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19840014" @default.
• W2029039557 hasPublicationYear "2009" @default.
• W2029039557 type Work @default.
• W2029039557 sameAs 2029039557 @default.
• W2029039557 citedByCount "32" @default.
• W2029039557 countsByYear W20290395572012 @default.
• W2029039557 countsByYear W20290395572013 @default.
• W2029039557 countsByYear W20290395572014 @default.
• W2029039557 countsByYear W20290395572016 @default.
• W2029039557 countsByYear W20290395572018 @default.
• W2029039557 countsByYear W20290395572019 @default.
• W2029039557 countsByYear W20290395572020 @default.
• W2029039557 countsByYear W20290395572021 @default.
• W2029039557 countsByYear W20290395572023 @default.
• W2029039557 crossrefType "journal-article" @default.
• W2029039557 hasAuthorship W2029039557A5001069772 @default.
• W2029039557 hasAuthorship W2029039557A5077333954 @default.
• W2029039557 hasConcept C121608353 @default.
• W2029039557 hasConcept C126322002 @default.
• W2029039557 hasConcept C141071460 @default.
• W2029039557 hasConcept C142724271 @default.
• W2029039557 hasConcept C143998085 @default.

• next