Matches in SemOpenAlex for { <https://semopenalex.org/work/W2029041471> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2029041471 endingPage "285" @default.
- W2029041471 startingPage "279" @default.
- W2029041471 abstract "The effects of N-(2,6-dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)-acetamide (DM-9384, nefiracetam), a cyclic derivative of GABA, were investigated in the carbon monoxide (CO)-induced amnesia model in mice using the passive avoidance task. Memory deficiency occurred when mice were exposed to CO before memory was completely consolidated after training (acute amnesia), at 7 days before training and 7 days after training (delayed amnesia). DM-9384 prolonged the step-down latency in mice with CO-induced amnesia. Scopolamine blocked the anti-amnesic effect of DM-9384 on delayed amnesia that had been induced by pre- or post-training exposure to CO. Bicuculline had a tendency to antagonize the anti-amnesic effect of DM-9384, but this tendency was not significant. Under these conditions, no significant change in the activity of choline acetyltransferase and glutamic acid decarboxylase was observed in the frontal cortex, striatum and hippocampus. These results suggest that DM-9384 potentiates cholinergic neuronal function and that it may modify acquisition and/or consolidation of memory." @default.
- W2029041471 created "2016-06-24" @default.
- W2029041471 creator A5009434663 @default.
- W2029041471 creator A5027520632 @default.
- W2029041471 creator A5055747865 @default.
- W2029041471 creator A5071121736 @default.
- W2029041471 creator A5088920500 @default.
- W2029041471 creator A5089387849 @default.
- W2029041471 date "1992-06-01" @default.
- W2029041471 modified "2023-09-26" @default.
- W2029041471 title "Involvement of the cholinergic system in the effects of nefiracetam (DM-9384) on carbon monoxide (CO)-induced acute and delayed amnesia" @default.
- W2029041471 cites W127251495 @default.
- W2029041471 cites W1483940173 @default.
- W2029041471 cites W1684853394 @default.
- W2029041471 cites W1775749144 @default.
- W2029041471 cites W1912564681 @default.
- W2029041471 cites W1965479899 @default.
- W2029041471 cites W1981127375 @default.
- W2029041471 cites W1985398722 @default.
- W2029041471 cites W1988378336 @default.
- W2029041471 cites W1988746120 @default.
- W2029041471 cites W1991693145 @default.
- W2029041471 cites W1995986030 @default.
- W2029041471 cites W1999913036 @default.
- W2029041471 cites W2038013895 @default.
- W2029041471 cites W2040393166 @default.
- W2029041471 cites W2070571957 @default.
- W2029041471 cites W2074636136 @default.
- W2029041471 cites W2079266652 @default.
- W2029041471 cites W2080493074 @default.
- W2029041471 cites W2095873344 @default.
- W2029041471 cites W2099768623 @default.
- W2029041471 doi "https://doi.org/10.1016/0014-2999(92)90371-a" @default.
- W2029041471 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1397012" @default.
- W2029041471 hasPublicationYear "1992" @default.
- W2029041471 type Work @default.
- W2029041471 sameAs 2029041471 @default.
- W2029041471 citedByCount "30" @default.
- W2029041471 countsByYear W20290414712018 @default.
- W2029041471 crossrefType "journal-article" @default.
- W2029041471 hasAuthorship W2029041471A5009434663 @default.
- W2029041471 hasAuthorship W2029041471A5027520632 @default.
- W2029041471 hasAuthorship W2029041471A5055747865 @default.
- W2029041471 hasAuthorship W2029041471A5071121736 @default.
- W2029041471 hasAuthorship W2029041471A5088920500 @default.
- W2029041471 hasAuthorship W2029041471A5089387849 @default.
- W2029041471 hasConcept C118552586 @default.
- W2029041471 hasConcept C126322002 @default.
- W2029041471 hasConcept C15744967 @default.
- W2029041471 hasConcept C169760540 @default.
- W2029041471 hasConcept C185592680 @default.
- W2029041471 hasConcept C198399640 @default.
- W2029041471 hasConcept C22885893 @default.
- W2029041471 hasConcept C2778615406 @default.
- W2029041471 hasConcept C2781161787 @default.
- W2029041471 hasConcept C42219234 @default.
- W2029041471 hasConcept C71924100 @default.
- W2029041471 hasConcept C98274493 @default.
- W2029041471 hasConceptScore W2029041471C118552586 @default.
- W2029041471 hasConceptScore W2029041471C126322002 @default.
- W2029041471 hasConceptScore W2029041471C15744967 @default.
- W2029041471 hasConceptScore W2029041471C169760540 @default.
- W2029041471 hasConceptScore W2029041471C185592680 @default.
- W2029041471 hasConceptScore W2029041471C198399640 @default.
- W2029041471 hasConceptScore W2029041471C22885893 @default.
- W2029041471 hasConceptScore W2029041471C2778615406 @default.
- W2029041471 hasConceptScore W2029041471C2781161787 @default.
- W2029041471 hasConceptScore W2029041471C42219234 @default.
- W2029041471 hasConceptScore W2029041471C71924100 @default.
- W2029041471 hasConceptScore W2029041471C98274493 @default.
- W2029041471 hasIssue "2" @default.
- W2029041471 hasLocation W20290414711 @default.
- W2029041471 hasLocation W20290414712 @default.
- W2029041471 hasOpenAccess W2029041471 @default.
- W2029041471 hasPrimaryLocation W20290414711 @default.
- W2029041471 hasRelatedWork W2038758804 @default.
- W2029041471 hasRelatedWork W2058054505 @default.
- W2029041471 hasRelatedWork W2071190410 @default.
- W2029041471 hasRelatedWork W2072640087 @default.
- W2029041471 hasRelatedWork W2090995969 @default.
- W2029041471 hasRelatedWork W2156266544 @default.
- W2029041471 hasRelatedWork W2393833614 @default.
- W2029041471 hasRelatedWork W2748952813 @default.
- W2029041471 hasRelatedWork W2754644051 @default.
- W2029041471 hasRelatedWork W2899084033 @default.
- W2029041471 hasVolume "216" @default.
- W2029041471 isParatext "false" @default.
- W2029041471 isRetracted "false" @default.
- W2029041471 magId "2029041471" @default.
- W2029041471 workType "article" @default.